Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2004.01.096 ◽

2004 ◽

Vol 14 (9) ◽

pp. 2357-2361 ◽

Author(s):

Francesco Abbate ◽

Angela Casini ◽

Andrea Scozzafava ◽

Claudiu T Supuran

Keyword(s):

Carbonic Anhydrase ◽

Crystallographic Structure ◽

Carbonic Anhydrase Inhibitors ◽

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Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide—two heads are better than one?

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(03)00508-0 ◽

2003 ◽

Vol 13 (16) ◽

pp. 2759-2763 ◽

Author(s):

Angela Casini ◽

Francesco Abbate ◽

Andrea Scozzafava ◽

Claudiu T Supuran

Keyword(s):

Carbonic Anhydrase ◽

Crystallographic Structure ◽

Carbonic Anhydrase Inhibitors ◽

X Ray ◽

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Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2003.11.014 ◽

2004 ◽

Vol 14 (2) ◽

pp. 337-341 ◽

Author(s):

Francesco Abbate ◽

Anita Coetzee ◽

Angela Casini ◽

Samuele Ciattini ◽

Andrea Scozzafava ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Antipsychotic Drug ◽

Crystallographic Structure ◽

Carbonic Anhydrase Inhibitors ◽

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Carbonic Anhydrase Inhibitors: X-ray Crystallographic Structure of the Adduct of Human Isozyme II with the Perfluorobenzoyl Analogue of Methazolamide. Implications for the Drug Design of Fluorinated Inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/1475636031000119337 ◽

2003 ◽

Vol 18 (4) ◽

pp. 303-308 ◽

Author(s):

Francesco Abbate ◽

Angela Casini ◽

Andrea Scozzafava ◽

Claudiu T. Supuran

Keyword(s):

Drug Design ◽

Carbonic Anhydrase ◽

Crystallographic Structure ◽

Carbonic Anhydrase Inhibitors ◽

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Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2003.09.064 ◽

2004 ◽

Vol 14 (1) ◽

pp. 231-234 ◽

Author(s):

Francesco Abbate ◽

Jean-Yves Winum ◽

Barry V.L. Potter ◽

Angela Casini ◽

Jean-Louis Montero ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Crystallographic Structure ◽

Steroid Sulfatase ◽

Carbonic Anhydrases ◽

Dual Inhibitor ◽

Carbonic Anhydrase Inhibitors ◽

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Carbonic anhydrase inhibitors: The X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2008.03.023 ◽

2008 ◽

Vol 18 (8) ◽

pp. 2669-2674 ◽

Author(s):

Anna Di Fiore ◽

Carlo Pedone ◽

Jochen Antel ◽

Harald Waldeck ◽

Andreas Witte ◽

...

Keyword(s):

Crystal Structure ◽

Carbonic Anhydrase ◽

Tight Binding ◽

Carbonic Anhydrase Inhibitors ◽

X Ray ◽

Binding Inhibitors

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Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: Solution and X-ray crystallographic studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2013.11.016 ◽

2014 ◽

Vol 22 (1) ◽

pp. 334-340 ◽

Author(s):

Murat Bozdag ◽

Marta Ferraroni ◽

Elisa Nuti ◽

Daniela Vullo ◽

Armando Rossello ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

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Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II–trithiocarbonate adduct—An inhibitor mimicking the sulfonamide and urea binding to the enzyme

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.11.124 ◽

2010 ◽

Vol 20 (2) ◽

pp. 474-478 ◽

Author(s):

Claudia Temperini ◽

Andrea Scozzafava ◽

Claudiu T. Supuran

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Ii ◽

Carbonic Anhydrase Inhibitors ◽

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Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine–benzenesulfonamides acting as carbonic anhydrase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2016.06.005 ◽

2016 ◽

Vol 24 (16) ◽

pp. 3643-3648 ◽

Author(s):

Daniela Vullo ◽

Claudiu T. Supuran ◽

Andrea Scozzafava ◽

Giuseppina De Simone ◽

Simona Maria Monti ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

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A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide

Inorganica Chimica Acta ◽

10.1016/s0020-1693(98)00077-2 ◽

1998 ◽

Vol 275-276 ◽

pp. 295-300 ◽

Author(s):

Fabrizio Briganti ◽

Valeria Iaconi ◽

Stefano Mangani ◽

Pierluigi Orioli ◽

Andrea Scozzafava ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Ternary Complex ◽

Carbonic Anhydrase Ii ◽

Crystallographic Structure ◽

X Ray ◽

Human Carbonic Anhydrase

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4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b01771 ◽

2016 ◽

Vol 59 (2) ◽

pp. 721-732 ◽

Author(s):

Benedetta Cornelio ◽

Marie Laronze-Cochard ◽

Mariangela Ceruso ◽

Marta Ferraroni ◽

Graham A. Rance ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Enzyme Inhibition ◽

Carbonic Anhydrase Inhibitors ◽

X Ray ◽

Human Carbonic Anhydrase

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