Initial structure–activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist

2004 ◽  
Vol 14 (11) ◽  
pp. 2735-2740 ◽  
Author(s):  
Brian H. Heasley ◽  
Renata Jarosz ◽  
Kevin R. Lynch ◽  
Timothy L. Macdonald
Keyword(s):  
Receptor Antagonist ◽  
Lysophosphatidic Acid ◽  
Initial Structure ◽  
Receptor Antagonists ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Structure Activity Relationships ◽  
High Affinity ◽  
Structure Activity

scholarly journals MP09-01 EFFECT OF ASP6432, A TYPE 1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST, ON URETHRAL FUNCTION DURING THE VOIDING PHASE IN RATS

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Kazuyuki Sakamoto ◽  
Yukiko Noguchi ◽  
Katsunori Imazumi ◽  
Koji Ueshima ◽  
Akiyoshi Ohtake ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Lysophosphatidic Acid ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Urethral Function

ChemInform Abstract: Synthesis and Initial Structure-Activity Relationships of a Novel Series of Imidazolo[1,2-a]pyrimid-5-ones as Potent GnRH Receptor Antagonists

ChemInform ◽  
2010 ◽  
Vol 33 (49) ◽  
pp. no-no
Author(s):  
Keith M. Wilcoxen ◽  
Yun-Fei Zhu ◽  
Patrick J. Connors Jr. ◽  
John Saunders ◽  
Timothy D. Gross ◽  
...  
Keyword(s):  
Gnrh Receptor ◽  
Initial Structure ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo

2012 ◽  
Vol 103 (6) ◽  
pp. 1099-1104 ◽  
Author(s):  
Mayumi Komachi ◽  
Koichi Sato ◽  
Masayuki Tobo ◽  
Chihiro Mogi ◽  
Takayuki Yamada ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Receptor Antagonist ◽  
Lysophosphatidic Acid ◽  
Cancer Invasion ◽  
Invasion And Metastasis ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Orally Active
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