Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors

2015 ◽  
Vol 25 (9) ◽  
pp. 1947-1951 ◽  
Author(s):  
Zhong Chen ◽  
Zhong-Chang Wang ◽  
Xiao-Qiang Yan ◽  
Peng-Fei Wang ◽  
Xiao-Yuan Lu ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Cox 2 ◽  
Cox 2 Inhibitors ◽  
Cox 1

scholarly journals Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors

2017 ◽  
Vol 25 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Deema A. Al-Turki ◽  
Mohamed A. Al-Omar ◽  
Laila A. Abou-zeid ◽  
Ihsan A. Shehata ◽  
Mohammed S. Al-Awady
Keyword(s):  
Molecular Modeling ◽  
Biological Evaluation ◽  
Cyclooxygenase 2 ◽  
Design Synthesis ◽  
Cox 2 ◽  
Cox 2 Inhibitors

scholarly journals Design, synthesis and biological evaluation of new 2-aminothiazole scaffolds as phosphodiesterase type 5 regulators and COX-1/COX-2 inhibitors

RSC Advances ◽  
2020 ◽  
Vol 10 (50) ◽  
pp. 29723-29736 ◽  
Author(s):  
Abdel Haleem M. Hussein ◽  
Ahmed A. Khames ◽  
Abu-Bakr A. El-Adasy ◽  
Ahmed A. Atalla ◽  
Mohamed Abdel-Rady ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Cox 2 ◽  
Phosphodiesterase Type ◽  
Cox 2 Inhibitors ◽  
Synthesis And Biological Evaluation ◽  
Cox 1

A new series of 2-aminothiazole derivatives was designed and prepared as phosphodiesterase type 5 (PDE5) regulators and COX-1/COX-2 inhibitors.

scholarly journals Design, Synthesis, Molecular Docking and Biological Evaluation of Novel Coumarin-Oxime Ether Derivatives as COX-2 Inhibitors

2017 ◽  
Vol 29 (11) ◽  
pp. 2559-2564
Author(s):  
M. Vijaya Bhargavi ◽  
P. Shashikala ◽  
M. Sumakanth ◽  
Shravan Kumar Gunda
Keyword(s):  
Molecular Docking ◽  
Biological Evaluation ◽  
Oxime Ether ◽  
Design Synthesis ◽  
Cox 2 ◽  
Cox 2 Inhibitors

Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors

2006 ◽  
Vol 14 (8) ◽  
pp. 2507-2517 ◽  
Author(s):  
Latifeh Navidpour ◽  
Hamed Shafaroodi ◽  
Khosrou Abdi ◽  
Mohsen Amini ◽  
Mohammad H. Ghahremani ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Cox 2 ◽  
Cox 2 Inhibitors ◽  
Synthesis And Biological Evaluation

2‐Mercapto Benzthiazole Coupled Benzyl Triazoles as New COX‐2 Inhibitors: Design, Synthesis, Biological Testing and Molecular Modeling Studies

2019 ◽  
Vol 4 (37) ◽  
pp. 11081-11092
Author(s):  
Satyanarayana Yatam ◽  
Surender Singh Jadav ◽  
Krishna Prasadh Gundla ◽  
Kalyani Paidikondala ◽  
Ashok Reddy Ankireddy ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Biological Testing ◽  
Design Synthesis ◽  
Modeling Studies ◽  
Molecular Modeling Studies ◽  
Cox 2 ◽  
Cox 2 Inhibitors
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