scholarly journals Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure–activity relationship study of a quinoline thiourea

2016 ◽  
Vol 26 (2) ◽  
pp. 630-635 ◽  
Author(s):  
Niamh Dolan ◽  
Declan P. Gavin ◽  
Ahmed Eshwika ◽  
Kevin Kavanagh ◽  
John McGinley ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Toxicity ◽  
Structure Activity ◽  
Relationship Study

scholarly journals PRELIMINARY STRUCTURE–ACTIVITY RELATIONSHIP STUDY OF HEPTAMETHINE INDOCYANINE DYES FOR TUMOR-TARGETED IMAGING

2013 ◽  
Vol 06 (01) ◽  
pp. 1350003 ◽  
Author(s):  
QINYUAN GUO ◽  
SHENGLIN LUO ◽  
QINGRONG QI ◽  
CHUNMENG SHI
Keyword(s):  
In Vivo Imaging ◽  
Near Infrared ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Targeted Imaging ◽  
Structure Activity ◽  
Relationship Study ◽  
Tumor Accumulation ◽  
Sar Study

Our research has identified a couple of near-infrared (NIR) heptamethine indocyanine dyes exhibiting preferential tumor accumulation property for in vivo imaging. On the basis of our foregoing work, we describe here a preliminary structure–activity relationship (SAR) study of 11 related heptamethine indocyanine dyes and several essential requirements of these structures for in vivo tumor-targeted imaging.

scholarly journals In Vivo Structure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

2010 ◽  
Vol 5 (2) ◽  
pp. 245-253 ◽  
Author(s):  
Jijun Hao ◽  
Joshua N. Ho ◽  
Jana A. Lewis ◽  
Kaleh A. Karim ◽  
R. Nathan Daniels ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study

Structure–activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection

RSC Advances ◽  
2015 ◽  
Vol 5 (96) ◽  
pp. 78760-78770 ◽  
Author(s):  
Fatemeh Sheikhi Mehrabadi ◽  
Ole Hirsch ◽  
Reiner Zeisig ◽  
Paola Posocco ◽  
Erik Laurini ◽  
...  
Keyword(s):  
In Silico ◽  
Gene Transfection ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Sirna Transfection ◽  
Structure Activity ◽  
Relationship Study

Structure–activity relationship studies were performed through in vitro, in silico, and in vivo analysis in order to evaluate the gene transfection potential of dendritic polyglycerolamines with different amine loadings.

Synthesis, in vitro/in vivo Antifungal Evaluation and Structure-Activity Relationship Study of 3(2H)-Pyridazinones

2011 ◽  
Vol 53 (10) ◽  
pp. 738-743
Author(s):  
László Károlyházy ◽  
Monica Freile ◽  
Massud Anwair ◽  
Gyula Beke ◽  
Fernando Giannini ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study
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