Fluorinated Diaryl Sulfides as Serotonin Transporter Ligands:  Synthesis, Structure−Activity Relationship Study, and in Vivo Evaluation of Fluorine-18-Labeled Compounds as PET Imaging Agents

2005 ◽  
Vol 48 (7) ◽  
pp. 2559-2570 ◽  
Author(s):  
Yiyun Huang ◽  
Sung-A Bae ◽  
Zhihong Zhu ◽  
Ningning Guo ◽  
Bryan L. Roth ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Pet Imaging ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Imaging Agents ◽  
Labeled Compounds ◽  
In Vivo Evaluation ◽  
Structure Activity ◽  
Relationship Study

scholarly journals PRELIMINARY STRUCTURE–ACTIVITY RELATIONSHIP STUDY OF HEPTAMETHINE INDOCYANINE DYES FOR TUMOR-TARGETED IMAGING

2013 ◽  
Vol 06 (01) ◽  
pp. 1350003 ◽  
Author(s):  
QINYUAN GUO ◽  
SHENGLIN LUO ◽  
QINGRONG QI ◽  
CHUNMENG SHI
Keyword(s):  
In Vivo Imaging ◽  
Near Infrared ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Targeted Imaging ◽  
Structure Activity ◽  
Relationship Study ◽  
Tumor Accumulation ◽  
Sar Study

Our research has identified a couple of near-infrared (NIR) heptamethine indocyanine dyes exhibiting preferential tumor accumulation property for in vivo imaging. On the basis of our foregoing work, we describe here a preliminary structure–activity relationship (SAR) study of 11 related heptamethine indocyanine dyes and several essential requirements of these structures for in vivo tumor-targeted imaging.

scholarly journals In Vivo Structure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

2010 ◽  
Vol 5 (2) ◽  
pp. 245-253 ◽  
Author(s):  
Jijun Hao ◽  
Joshua N. Ho ◽  
Jana A. Lewis ◽  
Kaleh A. Karim ◽  
R. Nathan Daniels ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study
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