(E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction

Guangcheng Wang; Zhiyun Peng; Shanshan Peng; Jie Qiu; Yongjun Li; Yanyu Lan

doi:10.1016/j.bmcl.2018.09.004

(E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2018.09.004 ◽

2018 ◽

Vol 28 (20) ◽

pp. 3350-3355 ◽

Cited By ~ 3

Author(s):

Guangcheng Wang ◽

Zhiyun Peng ◽

Shanshan Peng ◽

Jie Qiu ◽

Yongjun Li ◽

...

Keyword(s):

Molecular Docking ◽

In Silico ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Adme Prediction ◽

In Silico Adme Prediction ◽

Tubulin Polymerization Inhibitors

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Anticholinesterase activities of novel indole-based hydrazide-hydrazone derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.131398 ◽

2021 ◽

pp. 131398

Author(s):

Ebru Didem Coşar ◽

Efe Doğukan Dincel ◽

Sedanur Demiray ◽

Ece Sucularlı ◽

Ezgi Tüccaroğlu ◽

...

Keyword(s):

Molecular Docking ◽

In Silico ◽

Docking Study ◽

Biological Evaluation ◽

Molecular Docking Study ◽

Design Synthesis ◽

Adme Prediction ◽

In Silico Adme Prediction

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Antileishmanial activity of novel indolyl–coumarin hybrids: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.12.085 ◽

2016 ◽

Vol 26 (3) ◽

pp. 829-835 ◽

Cited By ~ 22

Author(s):

Jaiprakash N. Sangshetti ◽

Firoz A. Kalam Khan ◽

Abhishek A. Kulkarni ◽

Rajendra H. Patil ◽

Amol M. Pachpinde ◽

...

Keyword(s):

Molecular Docking ◽

In Silico ◽

Docking Study ◽

Biological Evaluation ◽

Antileishmanial Activity ◽

Molecular Docking Study ◽

Design Synthesis ◽

Adme Prediction ◽

In Silico Adme Prediction

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Antioxidant activity of novel imidazo[2,1-b]thiazole derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.104220 ◽

2020 ◽

Vol 103 ◽

pp. 104220 ◽

Cited By ~ 1

Author(s):

Efe Doğukan Dincel ◽

Elif Gürsoy ◽

Tugba Yilmaz-Ozden ◽

Nuray Ulusoy-Güzeldemirci

Keyword(s):

Antioxidant Activity ◽

Molecular Docking ◽

In Silico ◽

Docking Study ◽

Biological Evaluation ◽

Thiazole Derivatives ◽

Molecular Docking Study ◽

Design Synthesis ◽

Adme Prediction ◽

In Silico Adme Prediction

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Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors

Drug Development Research ◽

10.1002/ddr.21880 ◽

2021 ◽

Author(s):

Naglaa F. El‐Sayed ◽

Marwa El‐Hussieny ◽

Ewies F. Ewies ◽

Mohamed F. El Shehry ◽

Hanem M. Awad ◽

...

Keyword(s):

Molecular Docking ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Indole Derivatives ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors

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Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2016.05.051 ◽

2016 ◽

Vol 24 (16) ◽

pp. 3456-3463 ◽

Cited By ~ 8

Author(s):

Firoz A. Kalam Khan ◽

Rajendra H. Patil ◽

Devanand B. Shinde ◽

Jaiprakash N. Sangshetti

Keyword(s):

Molecular Docking ◽

In Silico ◽

Docking Study ◽

Biological Evaluation ◽

Peptide Deformylase ◽

Molecular Docking Study ◽

Adme Prediction ◽

In Silico Adme Prediction

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Design, biological evaluation, molecular docking study and in silico ADME prediction of novel imidazo[2,1-b]thiazole derivatives as a novel class of α-glucosidase inhibitors

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.131260 ◽

2021 ◽

pp. 131260

Author(s):

Efe Doğukan Dincel ◽

Gozde Hasbal-Celikok ◽

Tugba Yilmaz-Ozden ◽

Nuray Ulusoy-Güzeldemirci

Keyword(s):

Molecular Docking ◽

In Silico ◽

Docking Study ◽

Biological Evaluation ◽

Thiazole Derivatives ◽

Molecular Docking Study ◽

Adme Prediction ◽

Glucosidase Inhibitors ◽

In Silico Adme Prediction

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Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103565 ◽

2020 ◽

Vol 95 ◽

pp. 103565 ◽

Cited By ~ 7

Author(s):

Guangcheng Wang ◽

Wenjing Liu ◽

Zipeng Gong ◽

Yong Huang ◽

Yongjun Li ◽

...

Keyword(s):

Molecular Docking ◽

Anticancer Agents ◽

Docking Studies ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Molecular Docking Studies ◽

Chalcone Derivatives ◽

Diaryl Ether ◽

Tubulin Polymerization Inhibitors

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Synthesis, molecular docking, and in silico ADME prediction of some fused pyrazolo[1,5-a]pyrimidine and pyrazole derivatives as potential antimicrobial agents

Journal of the Iranian Chemical Society ◽

10.1007/s13738-021-02319-4 ◽

2021 ◽

Author(s):

Ashraf S. Hassan ◽

Nesrin M. Morsy ◽

Hassan M. Awad ◽

Ahmed Ragab

Keyword(s):

Molecular Docking ◽

In Silico ◽

Antimicrobial Agents ◽

Pyrazole Derivatives ◽

Adme Prediction ◽

In Silico Adme Prediction

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Design, Synthesis and Biological Evaluation of 1,4-Disubstituted-3,4-dihydroisoquinoline Compounds as New Tubulin Polymerization Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms160510173 ◽

2015 ◽

Vol 16 (12) ◽

pp. 10173-10184 ◽

Cited By ~ 1

Author(s):

Ling Zhang ◽

Yunlong Song ◽

Jingjing Huang ◽

Jia Liu ◽

Wenwen Zhu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of Novel Acridine and Quinoline Derivatives as Tubulin Polymerization Inhibitors with Anticancer Activities

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2021.116376 ◽

2021 ◽

pp. 116376

Author(s):

Yichang Ren ◽

Yong Ruan ◽

Binbin Cheng ◽

Ling Li ◽

Jin Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Tubulin Polymerization ◽

Quinoline Derivatives ◽

Anticancer Activities ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

Synthesis And Biological Evaluation

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