Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors

2020 ◽  
Vol 95 ◽  
pp. 103565 ◽  
Author(s):  
Guangcheng Wang ◽  
Wenjing Liu ◽  
Zipeng Gong ◽  
Yong Huang ◽  
Yongjun Li ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Anticancer Agents ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Design Synthesis ◽  
Molecular Docking Studies ◽  
Chalcone Derivatives ◽  
Diaryl Ether ◽  
Tubulin Polymerization Inhibitors

Synthesis, biological evaluation, and molecular docking studies of novel chalcone oxime derivatives as potential tubulin polymerization inhibitors

RSC Advances ◽  
2014 ◽  
Vol 4 (61) ◽  
pp. 32263-32275 ◽  
Author(s):  
Yan-Ting Wang ◽  
Ya-Juan Qin ◽  
Ya-Liang Zhang ◽  
Yu-Jing Li ◽  
Bing Rao ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Molecular Docking Studies ◽  
Oxime Derivatives ◽  
Tubulin Polymerization Inhibitors

Compounds of novel chalcone oxime derivatives containing different substituent groups were designed, synthesized and evaluated for the inhibitory activity against tubulin polymerization and cancer cell inhibitory activity.

Molecular docking studies and biological evaluation of chalcone based pyrazolines as tyrosinase inhibitors and potential anticancer agents

RSC Advances ◽  
2015 ◽  
Vol 5 (57) ◽  
pp. 46330-46338 ◽  
Author(s):  
Hua-Li Qin ◽  
Zhen-Peng Shang ◽  
Ibrahim Jantan ◽  
Oya Unsal Tan ◽  
Muhammad Ajaz Hussain ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Anticancer Agents ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Molecular Docking Studies ◽  
Tyrosinase Inhibitors

A series of synthetic chalcones and pyrazoline derivatives showed antityrosinase, anticancer and considerable tubulin polymerization activity.

Synthesis, biological evaluation and molecular docking studies of 1,3-benzoxazine derivatives as potential anticancer agents

2013 ◽  
Vol 22 (11) ◽  
pp. 5256-5266 ◽  
Author(s):  
Vikas Garg ◽  
Ankit Kumar ◽  
Anurag Chaudhary ◽  
Saurabh Agrawal ◽  
Praveen Tomar ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Anticancer Agents ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Molecular Docking Studies
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