Computational modelling of potent β-secretase (BACE1) inhibitors towards Alzheimer's disease treatment

Biophysical Chemistry ◽

10.1016/j.bpc.2020.106536 ◽

2021 ◽

Vol 270 ◽

pp. 106536

Author(s):

Samuel C. Ugbaja ◽

Zainab K. Sanusi ◽

Patrick Appiah-Kubi ◽

Monsurat M. Lawal ◽

Hezekiel M. Kumalo

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Computational Modelling ◽

Disease Treatment

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Huprine Y – tryptophan heterodimers with potential implication to Alzheimer’s disease treatment

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2021.128100 ◽

2021 ◽

pp. 128100

Author(s):

Eva Mezeiova ◽

Martina Hrabinova ◽

Vendula Hepnarova ◽

Daniel Jun ◽

Jana Janockova ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Disease Treatment ◽

Potential Implication

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In silico and in vitro anti-AChE activity investigations of constituents from Mytragyna speciosa for Alzheimer’s disease treatment

Journal of Computer-Aided Molecular Design ◽

10.1007/s10822-020-00372-4 ◽

2021 ◽

Author(s):

Wansiri Innok ◽

Asadhawut Hiranrat ◽

Netnapa Chana ◽

Thanyada Rungrotmongkol ◽

Panita Kongsune

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

In Silico ◽

Ache Activity ◽

Disease Treatment

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Astrocyte subtype-specific approach to Alzheimer's disease treatment

Neurochemistry International ◽

10.1016/j.neuint.2021.104956 ◽

2021 ◽

Vol 145 ◽

pp. 104956

Author(s):

Sukanya Sarkar ◽

Subhas C. Biswas

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Disease Treatment ◽

Specific Approach

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Scutellaria barbata Leaf Extract Mediated Gold Nanoparticles for Alzheimer’s Disease Treatment by Metal-Induced Amyloid β Aggregation Inhibition

Journal of Cluster Science ◽

10.1007/s10876-019-01735-0 ◽

2019 ◽

Vol 31 (6) ◽

pp. 1269-1273

Author(s):

Guoqing Wang ◽

Jingcun Dai ◽

Xinjian Lu

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Gold Nanoparticles ◽

Leaf Extract ◽

Disease Treatment ◽

Scutellaria Barbata ◽

Aggregation Inhibition

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Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer’s disease treatment

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.02.104 ◽

2013 ◽

Vol 23 (11) ◽

pp. 3467-3469 ◽

Author(s):

Seong Rim Byeon ◽

Hyunjin Vincent Kim ◽

Mijin Jeon ◽

Young Gil Ahn ◽

Maeng Sup Kim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Disease Treatment

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Acetylcholinesterase inhibitors from southern African plants: An overview of ethnobotanical, pharmacological potential and phytochemical research including and beyond Alzheimer's disease treatment

South African Journal of Botany ◽

10.1016/j.sajb.2018.09.011 ◽

2019 ◽

Vol 120 ◽

pp. 39-64 ◽

Author(s):

N.A. Masondo ◽

G.I. Stafford ◽

A.O. Aremu ◽

N.P. Makunga

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholinesterase Inhibitors ◽

Disease Treatment ◽

African Plants ◽

Pharmacological Potential

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Book Review Alzheimer's Disease: Treatment and long-term management Edited by Jeffrey L. Cummings and Bruce L. Miller. 390 pp. New York, Marcel Dekker, 1990. $125.

New England Journal of Medicine ◽

10.1056/nejm199009203231223 ◽

1990 ◽

Vol 323 (12) ◽

pp. 839-839

Author(s):

Richard Mayeux

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

New York ◽

Disease Treatment ◽

Term Management

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Discovery of 4′-OH-flurbiprofen Mannich base derivatives as potential Alzheimer’s disease treatment with multiple inhibitory activities

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2019.01.040 ◽

2019 ◽

Vol 27 (6) ◽

pp. 991-1001 ◽

Author(s):

Hongyan Liu ◽

Xiaoming Qiang ◽

Qing Song ◽

Wei Li ◽

Yuxi He ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mannich Base ◽

Disease Treatment ◽

Inhibitory Activities

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A new approach for Alzheimer's disease treatment through P-gp regulation via ibuprofen

Pathology - Research and Practice ◽

10.1016/j.prp.2018.08.011 ◽

2018 ◽

Vol 214 (11) ◽

pp. 1765-1771 ◽

Author(s):

Chengxiang Zhang ◽

Heng Qin ◽

Rui Zheng ◽

Yubang Wang ◽

Ting Yan ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Disease Treatment ◽

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Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.12.003 ◽

2019 ◽

Vol 163 ◽

pp. 394-402 ◽

Author(s):

Alessandra Bisi ◽

Raquel L. Arribas ◽

Matteo Micucci ◽

Roberta Budriesi ◽

Alessandra Feoli ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Calcium Channels ◽

Disease Treatment ◽

Gsk 3Β ◽

Neuronal Calcium Channels

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