Familial cholestasis: Progressive familial intrahepatic cholestasis, benign recurrent intrahepatic cholestasis and intrahepatic cholestasis of pregnancy

2010 ◽  
Vol 24 (5) ◽  
pp. 541-553 ◽  
Author(s):  
Wendy L. van der Woerd ◽  
Saskia W.C. van Mil ◽  
Janneke M. Stapelbroek ◽  
Leo W.J. Klomp ◽  
Stan F.J. van de Graaf ◽  
...  
2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Mariam Ayyash ◽  
Nicolina Smith ◽  
Madhurima Keerthy ◽  
Ashina Singh ◽  
Majid Shaman

Introduction. Benign recurrent intrahepatic cholestasis is a rare hepatologic disorder characterized by recurrent, self-limited episodes of severe pruritus, jaundice, and elevated bile acids. While there are guidelines for the management of intrahepatic cholestasis of pregnancy, the literature regarding benign recurrent intrahepatic cholestasis and pregnancy is limited. Case. A 29-year-old G1P0 woman, with history of liver toxicity, had elevated total serum bile acid levels and liver enzymes documented at 8 weeks of gestation and throughout her pregnancy. She had a reactive nonstress test just 3 days prior to her induction. Fetal demise was noted when she presented at 36 weeks for her induction. Conclusion. We recommend that women with elevated total serum bile acid early in pregnancy due to a separate entity relative to intrahepatic cholestasis of pregnancy be managed in a more individualized approach.


2013 ◽  
pp. 1-1
Author(s):  
Vanya Nikolova ◽  
Shadi Abu Hayyeh ◽  
Georgia Papacleovoulou ◽  
Malcolm Parker ◽  
Catherine Williamson

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