Differential Effects of Alpha Vs Beta Myosin Heavy Chain on the Kinetcs and Mechanics of Familial Hypertrophic Cardiomyopathy Mutations in the Myosin Regulatory Light Chain

Myosin Heavy Chain ◽

Heavy Chain ◽

Light Chain ◽

Regulatory Light Chain ◽

Differential Effects ◽

Cardiomyopathy Mutations

Familial Hypertrophic Cardiomyopathy Mutations of the Myosin Regulatory Light Chain Remove Myosin Load Sensitivity

Biophysical Journal ◽

10.1016/j.bpj.2009.12.1163 ◽

2010 ◽

Vol 98 (3) ◽

pp. 215a-216a

Author(s):

Michael J. Greenberg ◽

Katarzyna Kazmierczak ◽

Danuta Szczesna-Cordary ◽

Jeffrey R. Moore

Keyword(s):

Light Chain ◽

Regulatory Light Chain ◽

Cardiomyopathy Mutations

Myosin Regulatory Light Chain Phosphorylation Rescues Cardiac Dysfunction Caused by Familial Hypertrophic Cardiomyopathy-Linked Mutations

Biophysical Journal ◽

10.1016/j.bpj.2011.11.3037 ◽

2012 ◽

Vol 102 (3) ◽

pp. 557a

Author(s):

Priya Muthu ◽

Katarzyna Kazmierczak ◽

Wenrui Huang ◽

Ana I. Rojas ◽

Danuta Szczesna-Cordary

Keyword(s):

Light Chain ◽

Cardiac Dysfunction ◽

Regulatory Light Chain ◽

Regulatory Light Chain Phosphorylation

Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice

The FASEB Journal ◽

10.1096/fj.08-118182 ◽

2008 ◽

Vol 23 (3) ◽

pp. 855-865 ◽

Cited By ~ 48

Author(s):

W. Glenn L. Kerrick ◽

Katarzyna Kazmierczak ◽

Yuanyuan Xu ◽

Yingcai Wang ◽

Danuta Szczesna‐Cordary

Keyword(s):

Transgenic Mice ◽

Papillary Muscle ◽

Light Chain ◽

Muscle Fibers ◽

Regulatory Light Chain ◽

Ventricular Myosin

In Vitro Motility Studies of C-terminal Myosin Regulatory Light Chain Mutants Implicated in Familial Hypertrophic Cardiomyopathy

Biophysical Journal ◽

10.1016/j.bpj.2009.12.3920 ◽

2010 ◽

Vol 98 (3) ◽

pp. 715a

Author(s):

William M. Schmidt ◽

James Watt ◽

Katarzyna Kazmierczak ◽

Jeff Moore ◽

Danuta Szczesna-Cordary

Keyword(s):

Light Chain ◽

Regulatory Light Chain ◽

In Vitro Motility

Type II myosin regulatory light chain relieves auto-inhibition of myosin-heavy-chain function

Nature Cell Biology ◽

10.1038/35041107 ◽

2000 ◽

Vol 2 (11) ◽

pp. 855-858 ◽

Cited By ~ 63

Author(s):

Naweed I. Naqvi ◽

Kelvin C. Y. Wong ◽

Xie Tang ◽

Mohan K. Balasubramanian

Keyword(s):

Myosin Heavy Chain ◽

Heavy Chain ◽

Light Chain ◽

Regulatory Light Chain ◽

Type Ii ◽

Type Ii Myosin

Familial Hypertrophic Cardiomyopathy-linked Alterations in Ca2+Binding of Human Cardiac Myosin Regulatory Light Chain Affect Cardiac Muscle Contraction

Journal of Biological Chemistry ◽

10.1074/jbc.m307092200 ◽

2003 ◽

Vol 279 (5) ◽

pp. 3535-3542 ◽

Cited By ~ 50

Author(s):

Danuta Szczesna-Cordary ◽

Georgianna Guzman ◽

Shuk-Shin Ng ◽

Jiaju Zhao

Keyword(s):

Muscle Contraction ◽

Cardiac Muscle ◽

Light Chain ◽

Regulatory Light Chain ◽

Cardiac Myosin ◽

Cardiac Muscle Contraction

In vitro rescue study of a malignant familial hypertrophic cardiomyopathy phenotype by pseudo-phosphorylation of myosin regulatory light chain

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2013.12.011 ◽

2014 ◽

Vol 552-553 ◽

pp. 29-39 ◽

Cited By ~ 17

Author(s):

Priya Muthu ◽

Jingsheng Liang ◽

William Schmidt ◽

Jeffrey R. Moore ◽

Danuta Szczesna-Cordary

Keyword(s):

Light Chain ◽

Regulatory Light Chain ◽

Myosin Regulatory Light Chain

Familial Hypertrophic Cardiomyopathy-Linked Mutation (K104E) in the Myosin Regulatory Light Chain Affects Sarcomeric Structure and Function in Tg-Mice

Biophysical Journal ◽

10.1016/j.bpj.2013.11.254 ◽

2014 ◽

Vol 106 (2) ◽

pp. 33a

Author(s):

Wenrui Huang ◽

Jingsheng Liang ◽

Katarzyna Kazmierczak ◽

Priya Muthu ◽

Chen-Ching Yuan ◽

...

Keyword(s):

Light Chain ◽

Regulatory Light Chain ◽

Structure And Function ◽

And Function

Impact of Familial Hypertrophic Cardiomyopathy-Linked Mutations in the N-Terminus of the Myosin Regulatory Light Chain on the Calcium Based Motility

Biophysical Journal ◽

10.1016/j.bpj.2013.11.252 ◽

2014 ◽

Vol 106 (2) ◽

pp. 33a

Author(s):

Gerrie P. Farman ◽

Priya Mutha ◽

Katarzyna Kazmierczak ◽

Danuta Szczesna-Cordary ◽

Jeffery R. Moore

Keyword(s):

Light Chain ◽

Regulatory Light Chain ◽

N Terminus

Screening of the Cardiac Beta Myosin Heavy Chain Gene for the Linkage to Familial Hypertrophic Cardiomyopathy in a Korean Family

Korean Circulation Journal ◽

10.4070/kcj.1994.24.6.819 ◽

1994 ◽

Vol 24 (6) ◽

pp. 819

Author(s):

Jeong-Euy Park ◽

Cheong-Ho Lee ◽

Hae-Kyung Kim ◽

Jeong-Won Sohn ◽

Gil-Hong Park ◽

...

Keyword(s):

Myosin Heavy Chain ◽

Heavy Chain ◽

Chain Gene ◽

Heavy Chain Gene ◽

Myosin Heavy Chain Gene ◽

Korean Family