Mechanically-induced cortical spreading depression associated regional cerebral blood flow changes are blocked by Na+ ion channel blockade

2008 ◽  
Vol 1229 ◽  
pp. 27-36 ◽  
Author(s):  
Simon Akerman ◽  
Philip R. Holland ◽  
Peter J. Goadsby
Cephalalgia ◽  
1985 ◽  
Vol 5 (2_suppl) ◽  
pp. 43-46 ◽  
Author(s):  
Jes Olesen ◽  
Sissel Vorstrup ◽  
Martin Lauritzen

TIA is usually caused by embolism from a carotid stenosis. The stenosis has no hemodynamic significance, but recent studies of regional cerebral blood flow have indicated that this occurs in a few cases. Traditionally, TIA are not considered to cause cerebral damage, but CT-studies have revealed a number of silent infarcts and rCBF measurements have shown even more persistent abnormalities of blood flow. In classic migraine, alterations of rCBF are completely different, indicating a mechanism progressing in the cerebral cortex, probably the spreading depression of Leao. Similar blood flow changes are not seen in common migraine, where tomographic rCBF determinations have been normal.


1990 ◽  
Vol 15 (12) ◽  
pp. 904-907 ◽  
Author(s):  
BELKIS ERBAS ◽  
HAKAN KUMBASAR ◽  
G??NAYDIN ERBENGI ◽  
COSKUN BEKDIK

2003 ◽  
Vol 15 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Sergio Paradiso ◽  
Robert G. Robinson ◽  
Laura L. Boles Ponto ◽  
G. Leonard Watkins ◽  
Richard D. Hichwa

Sign in / Sign up

Export Citation Format

Share Document