Towards an efficient system for hyperthermia treatment of breast tumors

2022 ◽  
Vol 71 ◽  
pp. 103084
Author(s):  
N. Nizam-Uddin ◽  
Wazie M. Abdulkawi ◽  
Ibrahim Elshafiey ◽  
Abdel-Fattah A. Sheta
2017 ◽  
Vol 9 (6) ◽  
pp. 1317-1324 ◽  
Author(s):  
Johannes Crezee ◽  
Geertjan Van Tienhoven ◽  
Merel W. Kolff ◽  
Jan Sijbrands ◽  
Gerard Van Stam ◽  
...  

A dedicated hyperthermia (HT) system was designed for tumors in intact breast extending beyond the heating depth of our superficial 434 MHz antennas, consisting of a treatment bed fitted with a 50 cm × 40 cm × 16 cm temperature controlled open water bolus. The patient lies in prone position with the breast immersed in the water positioned in front of a 34 cm × 20 cm 70 MHz waveguide operating in the TE10 mode. E-field patterns were measured in a tissue-mimicking phantom. HT was applied once a week with the 70 MHz applicator for six patients treated with thermoradiotherapy for deep lesions of recurrent breast cancer or melanoma. Two 14-sensor thermocouple thermometry probes were placed in catheters to monitor the invasive temperature. Results: Phantom measurements showed sufficient penetration depth up to 10 cm depth. The combination of 300–900 W antenna power and a water temperature of 42°C was well tolerated for the entire session of 1 h and resulted in good tumor temperatures with T90 = 39.8°C, T50 = 41.1°C, and T10 = 42.2°C. No toxicity or complaints were associated with the heating. A water mattress and other measures were needed to assure a comfortable position throughout the treatment. Conclusion: the 70 MHz breast applicator system performed well and tumor temperatures were good.


2019 ◽  
Vol 77 ◽  
pp. 1-16 ◽  
Author(s):  
Saptarshi Mukherjee ◽  
Lalita Udpa ◽  
Satish Udpa ◽  
Edward J. Rothwell ◽  
Yiming Deng

Author(s):  
J Crezee ◽  
G van Tienhoven ◽  
M W Kolff ◽  
J Sijbrands ◽  
G van Stam ◽  
...  

Author(s):  
A Ciurea ◽  
A Arpasteuan ◽  
G Dindelegan ◽  
R Motocu ◽  
L Rogojan

2020 ◽  
pp. 25-31
Author(s):  
M. L. Mazo ◽  
O. E. Jacobs ◽  
O. S. Puchkova ◽  
M. V. Feldsherov ◽  
E. V. Kondratyev

The rate of detection of breast cancer by MRI, while other methods of radiological diagnosis are not sufficiently informative, ranges from 5.2 to 26.3 per cent. Suspicious breast tumors of category BI-RADS 4, 5 show morphological image-guided biopsy verification, in particular MRI with contrast. Purpose. To show the possibilities and features of carrying out MRI-guided vacuum breast biopsy, including after aesthetic breast augmentation. Material and methods. A comprehensive X-ray, ultrasound and MRI examination of 54 women aged between 28 and 70 years with different breast tumors was conducted. Of these, five were detected only by breast MRI with contrast, and were morphologically verified by MRI-guided vacuum aspiration biopsy. Results. 14 of the 54 patients with breast mass were diagnosed with breast cancer and 26 were diagnosed with benign diseases. The effectiveness of comprehensive examination and low-invasive high-tech MRI-guided procedures in early refined screening for breast cancer, including after aesthetic breast augmentation, has been demonstrated. MRI-guided vacuum-assisted breast biopsy is a fast, safe and accurate diagnostic method of morphological verification of suspicious breast tumors that do not have X-ray and ultrasound.


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