Letter to the Editor and Author Response for “A systematic review and meta-analysis of randomized trials evaluating the efficacy of autologous skin cell suspensions for re- epithelialization of acute partial thickness burn injuries and split-thickness skin graft donor sites” by Bairagi, et al

Burns ◽  
2021 ◽  
Author(s):  
Anjana Bairagi ◽  
Bronwyn Griffin ◽  
Tara Banani ◽  
Steven M McPhail ◽  
Roy Kimble ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skin Graft ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Burn Injuries ◽  
Split Thickness Skin Graft ◽  
Skin Cell ◽  
Partial Thickness Burn ◽  
Thickness Skin ◽  
Graft Donor

scholarly journals Polyurethane Versus Calcium Alginate Dressings for Split-Thickness Skin Graft Donor Site: A Systematic Review and Meta-Analysis

Cureus ◽  
2021 ◽  
Author(s):  
Abdulmalik Alsaif ◽  
Mohammad Karam ◽  
Ahmed A Aldubaikhi ◽  
Abdullah Alghufaily ◽  
Khaled Alhuwaishel ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skin Graft ◽  
Calcium Alginate ◽  
Meta Analysis ◽  
Donor Site ◽  
Split Thickness Skin Graft ◽  
Thickness Skin ◽  
Graft Donor

Biological versus non-biological dressings in the management of split-thickness skin-graft donor sites: a systematic review and meta-analysis

2020 ◽  
Vol 29 (10) ◽  
pp. 604-610
Author(s):  
Shafiq Rahman ◽  
Benjamin Langridge ◽  
Ahmed Al-Hadad ◽  
Rehman Ali Khan ◽  
Muhammad Hyder Junejo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Wound Healing ◽  
Skin Graft ◽  
Meta Analysis ◽  
Healing Time ◽  
Conclusive Evidence ◽  
Split Thickness Skin Graft ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Thickness Skin

Objective: There are currently no definitive guidelines regarding the management of split-thickness skin-graft (STSG) donor sites. The literature reports biological and non-biological dressings as the two main groups; however, there is no conclusive evidence regarding the ideal type. A systematic review and meta-analysis of existing clinical trials was performed to compare biological and non-biological dressings in managing STSG donor sites. Method: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement standards was used to conduct this study. Electronic databases including MEDLINE, Embase, CINAHL and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched by two authors (SR and BL). Data analysis was performed with RevMan 5.3. Results: In total, 10 studies, consisting of eight randomised controlled trials and two observational assessments, were identified. Wound healing time was faster with biological dressings compared to non-biological dressings (mean difference -5.44 days; p<0.05). A higher epithelialisation rate was also noted for biological dressings. There was no difference in the infection rate between the two study groups (odds ratio [OR] 0.39; 95% confidence interval [CI] 0.15–1.04) or wound exudation (OR 0.31; 95% CI 0.01–8.28). The pain level experienced during dressing changes in both groups was reported to be similar. Conclusion: The rate of epithelialisation and wound healing is greater for STSG donor sites when treated with biological dressings, but they offer no difference in terms of reducing pain, limiting infection or exudation.

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