Diastolic Dysfunction in Patients with Heart Failure and Preserved Ejection Fraction: A Population Based Study

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pp. S4 ◽  
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Veronique L. Roger ◽  
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...  
2006 ◽  
Vol 12 (6) ◽  
pp. S23
Author(s):  
Carolyn S.P. Lam ◽  
Veronique R. Roger ◽  
Richard J. Rodeheffer ◽  
Francesca Bursi ◽  
Margaret M. Redfield

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It is a previously unrecognized physiological mechanism of the heart that diastolic filling occurs with the help of hydraulics. In patients with heart failure with preserved ejection fraction, atrial dilatation may cause the net hydraulic force to work against cardiac filling, thus further augmenting diastolic dysfunction. In contrast, it may work favorably in patients with dilated ventricles, as in heart failure with reduced ejection fraction.


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