Familial Dilated Cardiomyopathy Caused by an Alpha-Tropomyosin Mutation: The Distinctive Natural History of Sarcomeric DCM

2009 ◽  
Vol 15 (6) ◽  
pp. S3
Author(s):  
Neal K. Lakdawala ◽  
Lisa Dellefave ◽  
Elizabeth Sparks ◽  
Allison Cirino ◽  
Steve Depalma ◽  
...  
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
Familial Dilated Cardiomyopathy ◽  
History Of

scholarly journals Natural history of familial dilated cardiomyopathy: the heart muscle disease registry of trieste

2002 ◽  
Vol 39 ◽  
pp. 149
Author(s):  
Andrea Di Lenarda ◽  
Elisa Carniel ◽  
Gastone Sabbadini ◽  
Mauro Driussi ◽  
Serena Rakar ◽  
...  
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
Heart Muscle ◽  
Muscle Disease ◽  
Disease Registry ◽  
Familial Dilated Cardiomyopathy ◽  
History Of

Natural History of Idiopathic Dilated Cardiomyopathy

1993 ◽  
pp. 26-42
Author(s):  
F. Camerini ◽  
A. Di Lenarda ◽  
G. Lardieri ◽  
L. Mestroni ◽  
A. Perkan ◽  
...  
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
Idiopathic Dilated Cardiomyopathy ◽  
History Of

Natural history of incidentally discovered, asymptomatic idiopathic dilated cardiomyopathy

1994 ◽  
Vol 74 (7) ◽  
pp. 737-739 ◽  
Author(s):  
Margaret M. Redfield ◽  
Bernard J. Gersh ◽  
Kent R. Bailey ◽  
Richard J. Rodeheffer
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
Idiopathic Dilated Cardiomyopathy ◽  
History Of

scholarly journals Natural history of idiopathic dilated cardiomyopathy: effect of referral bias and secular trend

1993 ◽  
Vol 22 (7) ◽  
pp. 1921-1926 ◽  
Author(s):  
Margaret M. Redfield ◽  
Bernard J. Gersh ◽  
Kent R. Bailey ◽  
David J. Ballard ◽  
Richard J. Rodeheffer
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
Secular Trend ◽  
Idiopathic Dilated Cardiomyopathy ◽  
History Of ◽  
Referral Bias

Natural history of abnormal conduction and its relation to prognosis in patients with dilated cardiomyopathy

1996 ◽  
Vol 53 (2) ◽  
pp. 163-170 ◽  
Author(s):  
Han B. Xiao ◽  
Craig Roy ◽  
Shinichi Fujimoto ◽  
Derek G. Gibson
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
History Of

scholarly journals Natural History of Dilated Cardiomyopathy in Children

2016 ◽  
Vol 5 (7) ◽  
Author(s):  
Ilaria Puggia ◽  
Marco Merlo ◽  
Giulia Barbati ◽  
Teisha J. Rowland ◽  
Davide Stolfo ◽  
...  
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
History Of

scholarly journals P3169Clinical characteristics and natural history of dilated cardiomyopathy due to BAG3 mutations

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
F Dominguez Rodriguez ◽  
S Cuenca ◽  
Z Bilinska ◽  
R Toro ◽  
P Charron ◽  
...  
Keyword(s):  
Natural History ◽  
Dilated Cardiomyopathy ◽  
History Of

Natural history of Alström syndrome in early childhood: Onset with dilated cardiomyopathy

1996 ◽  
Vol 128 (2) ◽  
pp. 225-229 ◽  
Author(s):  
Jacques L. Michaud ◽  
Elise Héon ◽  
Françoise Guilbert ◽  
Jacques Weill ◽  
Bernard Puech ◽  
...  
Keyword(s):  
Early Childhood ◽  
Natural History ◽  
Dilated Cardiomyopathy ◽  
Childhood Onset ◽  
Alström Syndrome ◽  
History Of ◽  
Alstrom Syndrome

scholarly journals Heterozygous desmin gene (DES) mutation contributes to familial dilated cardiomyopathy

2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110065
Author(s):  
Ying-shuo Huang ◽  
Yun-li Xing ◽  
Hong-wei Li
Keyword(s):  
Dilated Cardiomyopathy ◽  
Coronary Arteriography ◽  
Sequencing Analysis ◽  
Shortness Of Breath ◽  
Genetic Sequencing ◽  
Familial Dilated Cardiomyopathy ◽  
Increased Risk ◽  
History Of ◽  
Whole Heart ◽  
Cardiac Enlargement

Familial dilated cardiomyopathy (FDCM) is characterized by high genetic heterogeneity and an increased risk of heart failure or sudden cardiac death in adults. We report the case of a 62-year-old man with a 2-month history of shortness of breath during activity, without paroxysmal nocturnal dyspnea. The patient underwent a series of examinations including transthoracic echocardiography, coronary arteriography, transesophageal echocardiography, and myocardial perfusion imaging. After excluding secondary cardiac enlargement, he was diagnosed with dilated cardiomyopathy (DCM). His sister had also been diagnosed with DCM several years before. Genetic sequencing analysis revealed that the patient, his sister, and his son all had the same mutation in the desmin gene ( DES) (chr2-220785662, c.1010C>T). Genetic testing confirmed a heterozygous DES mutation contributing to FDCM. In this case, the etiology of the patient’s whole-heart enlargement was determined as FDCM with DES gene mutation. This is the first report to describe DES c.1010C>T as a cause of FDCM.

Sign in / Sign up

Export Citation Format

Share Document