Advancing the education in molecular diagnostics: The IFCC-Initiative “Clinical Molecular Biology Curriculum” (C-CMBC); A ten-year experience

2014 ◽  
Vol 436 ◽  
pp. 5-8 ◽  
Author(s):  
Evi Lianidou ◽  
Parviz Ahmad-Nejad ◽  
Andrea Ferreira-Gonzalez ◽  
Kenji Izuhara ◽  
Laura Cremonesi ◽  
...  
Keyword(s):  
Molecular Biology ◽  
Molecular Diagnostics ◽  
Biology Curriculum

Introducing climate change into the biochemistry and molecular biology curriculum

2020 ◽  
Author(s):  
Henry V. Jakubowski ◽  
Nicholas Bock ◽  
Lucas Busta ◽  
Matthew Pearce ◽  
Rebecca L. Roston ◽  
...  
Keyword(s):  
Climate Change ◽  
Molecular Biology ◽  
Biology Curriculum

scholarly journals Innovations in education of the medical molecular biology curriculum during the COVID ‐19 pandemic in China

2021 ◽  
Author(s):  
Caifeng Xie ◽  
Chunhong Huang ◽  
Xiaohong Yang ◽  
Daya Luo ◽  
Zhuoqi Liu ◽  
...  
Keyword(s):  
Molecular Biology ◽  
Biology Curriculum

scholarly journals Introducing Climate Change into the Biochemistry and Molecular Biology Curriculum

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Henry Jakubowski ◽  
Nicholas Bock ◽  
Lucas Busta ◽  
Matthew Pearce ◽  
Rebecca Roston ◽  
...  
Keyword(s):  
Climate Change ◽  
Molecular Biology ◽  
Biology Curriculum

scholarly journals Relevance of long non-coding RNAs in tumour biology

2012 ◽  
Vol 153 (38) ◽  
pp. 1494-1501 ◽  
Author(s):  
Zoltán Nagy ◽  
Diána Rita Szabó ◽  
Adrienn Zsippai ◽  
András Falus ◽  
Károly Rácz ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Molecular Biology ◽  
Molecular Diagnostics ◽  
Small Rnas ◽  
Molecular Processes ◽  
Major Fraction ◽  
Rna Molecules ◽  
Mediated Effects ◽  
Non Coding Rna ◽  
Non Coding Rnas

The discovery of the biological relevance of non-coding RNA molecules represents one of the most significant advances in contemporary molecular biology. It has turned out that a major fraction of the non-coding part of the genome is transcribed. Beside small RNAs (including microRNAs) more and more data are disclosed concerning long non-coding RNAs of 200 nucleotides to 100 kb length that are implicated in the regulation of several basic molecular processes (cell proliferation, chromatin functioning, microRNA-mediated effects, etc.). Some of these long non-coding RNAs have been associated with human tumours, including H19, HOTAIR, MALAT1, etc., the different expression of which has been noted in various neoplasms relative to healthy tissues. Long non-coding RNAs may represent novel markers of molecular diagnostics and they might even turn out to be targets of therapeutic intervention. Orv. Hetil., 2012, 153, 1494–1501.

Electron Microscopy in Molecular Biology

1967 ◽  
Vol 25 ◽  
pp. 2-3
Author(s):  
Cecil E. Hall
Keyword(s):  
Electron Microscopy ◽  
Molecular Biology ◽  
Noise Level ◽  
Molecular Structures ◽  
Material Structure ◽  
The Arts ◽  
Shadow Casting ◽  
Electron Image ◽  
High Degree ◽  
Very High

The visualization of organic macromolecules such as proteins, nucleic acids, viruses and virus components has reached its high degree of effectiveness owing to refinements and reliability of instruments and to the invention of methods for enhancing the structure of these materials within the electron image. The latter techniques have been most important because what can be seen depends upon the molecular and atomic character of the object as modified which is rarely evident in the pristine material. Structure may thus be displayed by the arts of positive and negative staining, shadow casting, replication and other techniques. Enhancement of contrast, which delineates bounds of isolated macromolecules has been effected progressively over the years as illustrated in Figs. 1, 2, 3 and 4 by these methods. We now look to the future wondering what other visions are waiting to be seen. The instrument designers will need to exact from the arts of fabrication the performance that theory has prescribed as well as methods for phase and interference contrast with explorations of the potentialities of very high and very low voltages. Chemistry must play an increasingly important part in future progress by providing specific stain molecules of high visibility, substrates of vanishing “noise” level and means for preservation of molecular structures that usually exist in a solvated condition.

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