scholarly journals FtsZ dynamics in bacterial division: What, how, and why?

2021 ◽  
Vol 68 ◽  
pp. 163-172
Author(s):  
Jordan M. Barrows ◽  
Erin D. Goley
Keyword(s):  
Bacterial Division

scholarly journals Myxococcus xanthus as a Model Organism for Peptidoglycan Assembly and Bacterial Morphogenesis

2021 ◽  
Vol 9 (5) ◽  
pp. 916
Author(s):  
Huan Zhang ◽  
Srutha Venkatesan ◽  
Beiyan Nan
Keyword(s):  
De Novo ◽  
Myxococcus Xanthus ◽  
Model Organism ◽  
Life Stages ◽  
Negative Bacterium ◽  
Ideal Model ◽  
Daughter Cells ◽  
Bacterial Division ◽  
Cell Shapes ◽  
Rare Opportunity

A fundamental question in biology is how cell shapes are genetically encoded and enzymatically generated. Prevalent shapes among walled bacteria include spheres and rods. These shapes are chiefly determined by the peptidoglycan (PG) cell wall. Bacterial division results in two daughter cells, whose shapes are predetermined by the mother. This makes it difficult to explore the origin of cell shapes in healthy bacteria. In this review, we argue that the Gram-negative bacterium Myxococcus xanthus is an ideal model for understanding PG assembly and bacterial morphogenesis, because it forms rods and spheres at different life stages. Rod-shaped vegetative cells of M. xanthus can thoroughly degrade their PG and form spherical spores. As these spores germinate, cells rebuild their PG and reestablish rod shape without preexisting templates. Such a unique sphere-to-rod transition provides a rare opportunity to visualize de novo PG assembly and rod-like morphogenesis in a well-established model organism.

Targeting the Bacterial Division Protein FtsZ

2016 ◽  
Vol 59 (15) ◽  
pp. 6975-6998 ◽  
Author(s):  
Katherine A. Hurley ◽  
Thiago M. A. Santos ◽  
Gabriella M. Nepomuceno ◽  
Valerie Huynh ◽  
Jared T. Shaw ◽  
...  
Keyword(s):  
Bacterial Division

Blocking bacterial division

2008 ◽  
Vol 1 (36) ◽  
pp. 866-866
Author(s):  
Tim Fulmer
Keyword(s):  
Bacterial Division

scholarly journals 3D super-resolution microscopy of bacterial division machinery

2016 ◽  
Vol 741 ◽  
pp. 012066 ◽  
Author(s):  
A D Vedyaykin ◽  
A V Sabantsev ◽  
I E Vishnyakov ◽  
N E Morozova ◽  
V S Polinovskaya ◽  
...  
Keyword(s):  
Super Resolution ◽  
Bacterial Division ◽  
Super Resolution Microscopy

scholarly journals An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation

2019 ◽  
Vol 29 (9) ◽  
pp. 1460-1470.e4 ◽  
Author(s):  
Patrick J. Lariviere ◽  
Christopher R. Mahone ◽  
Gustavo Santiago-Collazo ◽  
Matthew Howell ◽  
Allison K. Daitch ◽  
...  
Keyword(s):  
Cell Wall ◽  
Bacterial Division

scholarly journals Human Neutrophil Calprotectin Reduces the Susceptibility of Borrelia burgdorferi to Penicillin

2006 ◽  
Vol 74 (4) ◽  
pp. 2468-2472 ◽  
Author(s):  
Ruth R. Montgomery ◽  
Kimberly Schreck ◽  
Xiaomei Wang ◽  
Stephen E. Malawista
Keyword(s):  
Lyme Disease ◽  
Borrelia Burgdorferi ◽  
Polymorphonuclear Leukocyte ◽  
Human Neutrophil ◽  
Penicillin G ◽  
Cytoplasmic Protein ◽  
Bacterial Division ◽  
Therapeutic Doses

ABSTRACT Borrelia burgdorferi, the spirochetal agent of Lyme disease, is susceptible to killing by a variety of polymorphonuclear leukocyte (PMN) components. Some are most effective against metabolically active B. burgdorferi. The abundant PMN cytoplasmic protein calprotectin, elevated 10- to 100-fold in inflammation, inhibits the growth of spirochetes through chelation of the essential cation, Zn. Since the action of some therapeutic antibiotics depends on bacterial division, we investigated the antibiotic sensitivities of spirochetes in calprotectin. In physiologic calprotectin, B. burgdorferi is not eliminated by therapeutic doses of penicillin G; in contrast, doxycycline is effective. Calprotectin may modify the clearance of spirochetes at sites of inflammation.

You Are What You Eat: Metabolic Control of Bacterial Division

2016 ◽  
Vol 24 (3) ◽  
pp. 181-189 ◽  
Author(s):  
Leigh G. Monahan ◽  
Elizabeth J. Harry
Keyword(s):  
Metabolic Control ◽  
Bacterial Division
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