Ex vivo expansion of regulatory T cells from long-term Belatacept-treated kidney transplant patients restores their phenotype and suppressive function but not their FOXP3 TSDR demethylation status

2020 ◽  
Vol 348 ◽  
pp. 104044
Author(s):  
A. Cortés-Hernández ◽  
E. Alvarez-Salazar ◽  
S. Arteaga-Cruz ◽  
J. Alberu-Gómez ◽  
G. Soldevila
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Kidney Transplant ◽  
Ex Vivo ◽  
Ex Vivo Expansion ◽  
Suppressive Function ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion

2010 ◽  
Vol 136 (3) ◽  
pp. 329-337 ◽  
Author(s):  
Tinghua Cao ◽  
Sally E. Wenzel ◽  
William A. Faubion ◽  
Gregory Harriman ◽  
Li Li
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Ex Vivo ◽  
Ex Vivo Expansion ◽  
Suppressive Function ◽  
Immune Mediated

Characterization of CD28−CD4+ T cells in living kidney transplant patients with long-term allograft acceptance

2001 ◽  
Vol 62 (12) ◽  
pp. 1335-1345 ◽  
Author(s):  
Masashi Kato ◽  
Tetsuya Matsuguchi ◽  
Yoshinari Ono ◽  
Ryohei Hattori ◽  
Shinichi Ohshima ◽  
...  
Keyword(s):  
T Cells ◽  
Kidney Transplant ◽  
Cd4 T Cells ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals The impact of induction therapy on the homeostasis and function of regulatory T cells in kidney transplant patients

2014 ◽  
Vol 29 (8) ◽  
pp. 1587-1597 ◽  
Author(s):  
A. P. Bouvy ◽  
M. Klepper ◽  
M. M. L. Kho ◽  
K. Boer ◽  
M. G. H. Betjes ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Kidney Transplant ◽  
Induction Therapy ◽  
Transplant Patients ◽  
Kidney Transplant Patients ◽  
And Function ◽  
The Impact

Quantification of Circulating Regulatory T Cells by Flow Cytometry in Kidney Transplant Patients After Basiliximab Induction Therapy

2010 ◽  
Vol 89 (3) ◽  
pp. 366-368 ◽  
Author(s):  
Farida Abadja ◽  
Eric Alamartine ◽  
François Berthoux ◽  
Christophe Mariat ◽  
Christian Genin ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
T Cells ◽  
Regulatory T Cells ◽  
Kidney Transplant ◽  
Induction Therapy ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Peripheral Blood Regulatory T Cells Are Diminished in Kidney-Transplant Patients with Chronic Allograft Nephropathy

2018 ◽  
Vol 102 ◽  
pp. S144
Author(s):  
Gloria Queipo ◽  
Marco Antonio Carmona ◽  
Luis-Antonio García Mosqueda ◽  
Luis García-Covarrubias ◽  
Miguel Angel Fonseca-Sánchez ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Kidney Transplant ◽  
Peripheral Blood ◽  
Chronic Allograft Nephropathy ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals The effect of rabbit anti-thymocyte globulin induction therapy on regulatory T cells in kidney transplant patients

2009 ◽  
Vol 24 (5) ◽  
pp. 1635-1644 ◽  
Author(s):  
V. D. K. D. Sewgobind ◽  
M. M. L. Kho ◽  
L. J. W. van der Laan ◽  
T. K. Hendrikx ◽  
T. van Dam ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Kidney Transplant ◽  
Induction Therapy ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Kinetic analysis reveals potency of CD4+ CD25bright+ regulatory T-cells in kidney transplant patients

2007 ◽  
Vol 18 (2) ◽  
pp. 159-165 ◽  
Author(s):  
J.H.L. Velthuis ◽  
D.A. Hesselink ◽  
T.K. Hendrikx ◽  
B.J. van der Mast ◽  
M. Klepper ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Kinetic Analysis ◽  
Kidney Transplant ◽  
Transplant Patients ◽  
Kidney Transplant Patients

Peripheral Blood Regulatory T Cells Are Diminished in Kidney Transplant Patients With Chronic Allograft Nephropathy

2018 ◽  
Vol 50 (2) ◽  
pp. 444-448 ◽  
Author(s):  
M.A. Carmona-Escamilla ◽  
G. Queipo ◽  
L.A. García-Mosqueda ◽  
L. García-Covarrubias ◽  
M.A. Fonseca-Sánchez ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Kidney Transplant ◽  
Peripheral Blood ◽  
Chronic Allograft Nephropathy ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals Methylation of FOXP3 TSDR Underlies the Impaired Suppressive Function of Tregs from Long-term Belatacept-Treated Kidney Transplant Patients

2017 ◽  
Vol 8 ◽  
Author(s):  
Evelyn Katy Alvarez Salazar ◽  
Arimelek Cortés-Hernández ◽  
Germán Rodrigo Alemán-Muench ◽  
Josefina Alberú ◽  
Jesús R. Rodríguez-Aguilera ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Suppressive Function ◽  
Transplant Patients ◽  
Kidney Transplant Patients
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