TGFβ1 induces endometrial cancer cell adhesion and migration by up-regulating integrin αvβ3 via SMAD-independent MEK-ERK1/2 signaling

2017 ◽  
Vol 34 ◽  
pp. 92-101 ◽  
Author(s):  
Siyuan Xiong ◽  
Christian Klausen ◽  
Jung-Chien Cheng ◽  
Peter C.K. Leung
Oncogene ◽  
2020 ◽  
Vol 39 (18) ◽  
pp. 3666-3679 ◽  
Author(s):  
Mario De Piano ◽  
Valeria Manuelli ◽  
Giorgia Zadra ◽  
Jonathan Otte ◽  
Per-Henrik D. Edqvist ◽  
...  

2019 ◽  
Vol 72 (3) ◽  
pp. 528-537 ◽  
Author(s):  
Jens Mani ◽  
Jens Neuschäfer ◽  
Christian Resch ◽  
Jochen Rutz ◽  
Sebastian Maxeiner ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Toshiyuki Murai

Lipid rafts are cholesterol-enriched microdomains of the cell membrane and possess a highly dynamic nature. They have been involved in various cellular functions including the regulation of cell adhesion and membrane signaling through proteins within lipid rafts. The dynamic features of the cancer cell surface may modulate the malignant phenotype of cancer, including adhesion disorders and aggressive phenotypes of migration and invasion. Recently, it was demonstrated that lipid rafts play critical roles in cancer cell adhesion and migration. This article summarizes the important roles of lipid rafts in cancer cell adhesion and migration, with a focus on the current state of knowledge. This article will improve the understanding of cancer progression and lead to the development of novel targets for cancer therapy.


Biomaterials ◽  
2019 ◽  
Vol 198 ◽  
pp. 95-106 ◽  
Author(s):  
Siyoung Choi ◽  
Jens Friedrichs ◽  
Young Hye Song ◽  
Carsten Werner ◽  
Lara A. Estroff ◽  
...  

Oncotarget ◽  
2015 ◽  
Vol 6 (31) ◽  
pp. 31659-31673 ◽  
Author(s):  
Siyuan Xiong ◽  
Christian Klausen ◽  
Jung-Chien Cheng ◽  
Hua Zhu ◽  
Peter C.K. Leung

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