JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks

Cell Reports ◽

10.1016/j.celrep.2016.08.006 ◽

2016 ◽

Vol 16 (10) ◽

pp. 2641-2650 ◽

Author(s):

Michael Van Meter ◽

Matthew Simon ◽

Gregory Tombline ◽

Alfred May ◽

Timothy D. Morello ◽

...

Keyword(s):

Oxidative Stress ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1111919109 ◽

2011 ◽

Vol 108 (52) ◽

pp. 21105-21110 ◽

Author(s):

M. Bauer ◽

M. Goldstein ◽

M. Christmann ◽

H. Becker ◽

D. Heylmann ◽

...

Keyword(s):

Oxidative Stress ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Human Monocytes ◽

Dna Double Strand Break ◽

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Elevated presence of retrotransposons at sites of DNA double strand break repair in mouse models of metabolic oxidative stress and MYC-induced lymphoma

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis ◽

10.1016/j.mrfmmm.2004.01.005 ◽

2004 ◽

Vol 548 (1-2) ◽

pp. 117-125 ◽

Author(s):

Lynne D. Rockwood ◽

Klaus Felix ◽

Siegfried Janz

Keyword(s):

Oxidative Stress ◽

Mouse Models ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair ◽

Metabolic Oxidative Stress

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Faculty Opinions recommendation of Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017512.204275 ◽

2004 ◽

Author(s):

Michael B Yaffe

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.12871066 ◽

2011 ◽

Author(s):

Claire Wyman

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.11019054 ◽

2011 ◽

Author(s):

Hao Wu ◽

Jixi Li

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1089242.542442 ◽

2007 ◽

Author(s):

Stephen Jackson

Keyword(s):

Chromatin Structure ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Structure Modulation ◽

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Faculty Opinions recommendation of Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104438.560671 ◽

2008 ◽

Author(s):

Carlos Telleria

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of A role for small RNAs in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14263986.790202827 ◽

2012 ◽

Author(s):

Traci Hall

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of A role for small RNAs in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14263986.15779121 ◽

2012 ◽

Author(s):

Luc DesGroseillers

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717988297.793472681 ◽

2013 ◽

Author(s):

Yamini Dalal

Keyword(s):

Chromatin Remodeling ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Download Full-text