Bridging the Gap Between Host Immune Response and Intestinal Dysbiosis in Inflammatory Bowel Disease: Does Immunoglobulin A Mark the Spot?

2015 ◽  
Vol 13 (5) ◽  
pp. 842-846 ◽  
Author(s):  
Jason M. Shapiro ◽  
Judy H. Cho ◽  
Bruce E. Sands ◽  
Neal S. LeLeiko
Keyword(s):  
Inflammatory Bowel Disease ◽  
Immune Response ◽  
Bowel Disease ◽  
Immunoglobulin A ◽  
Host Immune Response ◽  
Intestinal Dysbiosis ◽  
Inflammatory Bowel

8 ROLE OF THE HOST IMMUNE RESPONSE TO ENTERIC PROKARYOTIC VIRUSES IN INFLAMMATORY BOWEL DISEASE

2020 ◽  
Vol 158 (3) ◽  
pp. S68-S69
Author(s):  
Julia Angkeow ◽  
Daniel Monaco ◽  
Scott Handley ◽  
H.B. Larman
Keyword(s):  
Inflammatory Bowel Disease ◽  
Immune Response ◽  
Bowel Disease ◽  
Host Immune Response ◽  
Inflammatory Bowel

scholarly journals Host Immune Response to Clostridium difficile Infection in Inflammatory Bowel Disease Patients

2016 ◽  
Vol 22 (4) ◽  
pp. 853-861 ◽  
Author(s):  
Michelle Hughes ◽  
Taha Qazi ◽  
Adam Berg ◽  
Janice Weinberg ◽  
Xinhua Chen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Immune Response ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Bowel Disease ◽  
Host Immune Response ◽  
Inflammatory Bowel

scholarly journals Roles of Gut Bacteriophages in the Pathogenesis and Treatment of Inflammatory Bowel Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Lingling Qv ◽  
Sunbing Mao ◽  
Yongjun Li ◽  
Jia Zhang ◽  
Lanjuan Li
Keyword(s):  
Inflammatory Bowel Disease ◽  
Immune Response ◽  
Bowel Disease ◽  
Bacterial Population ◽  
Molecular Mechanisms ◽  
Host Immune Response ◽  
Intestinal Microbiome ◽  
Inflammatory Bowel ◽  
Main Factors

Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, are chronic, relapsing intestinal inflammatory disorders. Although the molecular mechanisms governing the pathogenesis of IBD are not completely clear, the main factors are presumed to be a complex interaction between genetic predisposition, host immune response and environmental exposure, especially the intestinal microbiome. Currently, most studies have focused on the role of gut bacteria in the onset and development of IBD, whereas little attention has been paid to the enteroviruses. Among of them, viruses that infect prokaryotes, called bacteriophages (phages) occupy the majority (90%) in population. Moreover, several recent studies have reported the capability of regulating the bacterial population in the gut, and the direct and indirect influence on host immune response. The present review highlights the roles of gut phages in IBD pathogenesis and explores the potentiality of phages as a therapeutic target for IBD treatment.

Immunoglobulin A Targets a Unique Subset of the Microbiota in Inflammatory Bowel Disease

2021 ◽  
Author(s):  
Jason M. Shapiro ◽  
Marcel R. de Zoete ◽  
Noah W. Palm ◽  
Yaro Laenen ◽  
Rene Bright ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Immunoglobulin A ◽  
Inflammatory Bowel

scholarly journals Effects of Immunosuppressants on Immune Response to Vaccine in Inflammatory Bowel Disease

2015 ◽  
Vol 128 (6) ◽  
pp. 835-838 ◽  
Author(s):  
Yuan Cao ◽  
Di Zhao ◽  
An-Tao Xu ◽  
Jun Shen ◽  
Zhi-Hua Ran
Keyword(s):  
Inflammatory Bowel Disease ◽  
Immune Response ◽  
Bowel Disease ◽  
Inflammatory Bowel

scholarly journals Intestinal dysbiosis in inflammatory bowel disease associated with primary immunodeficiency

2019 ◽  
Vol 143 (2) ◽  
pp. 775-778.e6 ◽  
Author(s):  
Harry Sokol ◽  
Nizar Mahlaoui ◽  
Claire Aguilar ◽  
Perrine Bach ◽  
Olivier Join-Lambert ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Primary Immunodeficiency ◽  
Bowel Disease ◽  
Intestinal Dysbiosis ◽  
Inflammatory Bowel
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