Enantioselective extraction of phenylsuccinic acid in aqueous two-phase systems based on acetone and β -cyclodextrin derivative: Modeling and optimization through response surface methodology

2016 ◽  
Vol 1467 ◽  
pp. 490-496 ◽  
Author(s):  
Jun Wang ◽  
Qi Liu ◽  
Liya Rong ◽  
Hua Yang ◽  
Feipeng Jiao ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Two Phase ◽  
Modeling And Optimization ◽  
Cyclodextrin Derivative ◽  
Phenylsuccinic Acid ◽  
Aqueous Two Phase Systems ◽  
Enantioselective Extraction ◽  
Phase Systems

Purification of CBS 819.72 α-amylase by aqueous two-phase systems: Modelling using Response Surface Methodology

2009 ◽  
Vol 46 (3) ◽  
pp. 306-312 ◽  
Author(s):  
Radhouane Kammoun ◽  
Hichem Chouayekh ◽  
Hajeur Abid ◽  
Belgacem Naili ◽  
Samir Bejar
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Two Phase ◽  
Aqueous Two Phase Systems ◽  
Systems Modelling ◽  
Phase Systems

scholarly journals Enantioselective Extraction of Phenylalanine Enantiomers Using Environmentally Friendly Aqueous Two-Phase Systems

Processes ◽  
2018 ◽  
Vol 6 (11) ◽  
pp. 212 ◽  
Author(s):  
Danyu Sun ◽  
Runping Wang ◽  
Fenfang Li ◽  
Lianglei Liu ◽  
Zhijian Tan
Keyword(s):  
Ionic Liquids ◽  
Environmentally Friendly ◽  
Deep Eutectic Solvents ◽  
Chiral Selector ◽  
Extraction Temperature ◽  
Two Phase ◽  
Aqueous Two Phase Systems ◽  
Enantioselective Extraction ◽  
Chiral Extraction ◽  
Phase Systems

(1) Background: The environmentally friendly choline-amino acid ionic liquids (ChAAILs) and deep eutectic solvents (DESs) have been used as excellent alternatives to volatile organic compounds (VOCs) and ionic liquids (ILs) in recent years; (2) Methods: Thus, ChAAILs/salt and DESs/salt aqueous two-phase systems (ATPSs) were developed for the chiral extraction of phenylalanine enantiomers. The optimum ATPS of [Ch][L-Pro]/K3PO4 was chosen, and the influencing parameters were investigated, including ChAAILs concentration, salt concentration, chiral selector concentration, extraction temperature, phenylalanine concentration, and system pH; (3) Results: The phenylalanine enantiomers were mainly extracted into the top phase (ChAAIL-rich phase), meanwhile, the (S)-phenylalanine [(S)-Phe)] was preferentially recognized by the chiral selector in the top phase. The maximum separation factor (α) of 2.05 was obtained under the optimal conditions; and (4) Conclusions: This ATPS that was used for the chiral extraction of enantiomers is much more environmentally friendly, simple, and rapid, and has the potential to be used in the enantioselective extraction of other enantiomers.

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