Sporadic Creutzfeldt–Jakob disease presenting as nonconvulsive status epilepticus case report and review of the literature

AbstractMetronidazole-induced encephalopathy is a rare toxic encephalopathy secondary to the common use to this antimicrobial drug. It has been reported mainly in adult patients but only rarely in children. Owing to possible devastating complication of this disease, clinicians should have a higher index of suspicion for encephalopathic patients on metronidazole therapy. Here, we report a 5-month-old infant with metronidazole-induced encephalopathy presenting with nonconvulsive status epilepticus. A review of the literature in pediatric, as well as adult metronidazole-induced encephalopathy, is also provided.

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Creutzfeldt-Jakob Disease Presenting as Nonconvulsive Status Epilepticus

Case Reports in Neurological Medicine ◽

10.1155/2018/3092018 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Aleksei Rakitin ◽

Riina Vibo ◽

Vaiko Veikat ◽

Anne Õunapuu ◽

Aive Liigant ◽

...

Keyword(s):

Case Report ◽

Status Epilepticus ◽

Clinical Presentation ◽

Epileptiform Activity ◽

Epileptic Activity ◽

Accurate Diagnosis ◽

Morphological Features ◽

Nonconvulsive Status Epilepticus ◽

Spongiform Encephalopathy ◽

Jakob Disease

Creutzfeldt-Jakob disease is a rare, rapidly progressive spongiform encephalopathy in humans. EEG plays an important role in diagnosing this disease. In some patients, epileptic activity and encephalopathy from various aetiologies may share morphological features on EEG. This similarity could create difficulties in EEG interpretation, especially if the patient presents with disturbed consciousness. In this case report, a 74-year-old female with Creutzfeldt-Jakob disease presented initially with rapidly progressive impairment of consciousness and focal epileptiform activity on EEG. An EEG performed 25 days later showed periodic sharp-wave complexes with triphasic morphology at a rate of 0.5 Hz, compatible with a diagnosis of Creutzfeldt-Jakob disease. Based on these results, we recommend that a diagnosis of Creutzfeldt-Jakob disease be considered in patients presenting with a rapid deterioration of consciousness and a clinical presentation of nonconvulsive status epilepticus. Monitoring these patients with serial EEGs could be useful to establish an accurate diagnosis.

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Sporadic Creutzfeldt–Jakob disease with tau pathology mimicking new‐onset refractory non‐convulsive status epilepticus: Case report and review of the literature

European Journal of Neurology ◽

10.1111/ene.14624 ◽

2020 ◽

Author(s):

Alicia Gonzalez‐Martinez ◽

Sonia Quintas ◽

Nuria Redondo ◽

Laura Casado‐Fernández ◽

José Vivancos

Keyword(s):

Case Report ◽

Status Epilepticus ◽

Convulsive Status Epilepticus ◽

Review Of The Literature ◽

Tau Pathology ◽

Jakob Disease ◽

New Onset

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Baclofen intoxication: a “fun drug” causing deep coma and nonconvulsive status epilepticus—a case report and review of the literature

European Journal of Pediatrics ◽

10.1007/s00431-012-1780-y ◽

2012 ◽

Vol 171 (10) ◽

pp. 1541-1547 ◽

Cited By ~ 28

Author(s):

Guido F. Weißhaar ◽

Marc Hoemberg ◽

Katja Bender ◽

Ursula Bangen ◽

Peter Herkenrath ◽

...

Keyword(s):

Case Report ◽

Status Epilepticus ◽

Nonconvulsive Status Epilepticus ◽

Deep Coma ◽

Review Of The Literature

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Norovirus Causes Pediatric Encephalopathy and Status Epilepticus: A Case Report and Review of the Literature

Journal of Pediatric Epilepsy ◽

10.1055/s-0041-1725990 ◽

2021 ◽

Author(s):

Gabriela Tantillo ◽

Navyamani Kagita ◽

Maite LaVega-Talbott ◽

Anuradha Singh ◽

David Kaufman

Keyword(s):

Magnetic Resonance Imaging ◽

Case Report ◽

Status Epilepticus ◽

Magnetic Resonance ◽

Review Of The Literature ◽

Resonance Imaging ◽

Common Cause ◽

Diffusion Restriction ◽

Neurologic Impairment ◽

Norovirus Gastroenteritis

AbstractNorovirus is a common cause of acute gastroenteritis outbreaks worldwide. The disease can present with varying degrees of neurologic impairment from benign convulsions to rare cases of severe encephalopathy. We describe a case report of a North American infant who presented with norovirus gastroenteritis, status epilepticus, severe encephalopathy, and abnormal but reversible diffusion restriction changes on magnetic resonance imaging of brain.

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Catatonia, beyond a psychiatric syndrome

Dementia & Neuropsychologia ◽

10.1590/1980-57642016dn11-020015 ◽

2017 ◽

Vol 11 (2) ◽

pp. 209-212

Author(s):

Nathália Stela Visoná de Figueiredo ◽

Débora Bartzen Moraes Angst ◽

Antônio de Matos Lima Neto ◽

Michel Ferreira Machado ◽

Maria Sheila Guimarães Rocha ◽

...

Keyword(s):

Case Report ◽

Status Epilepticus ◽

Clinical Manifestation ◽

Sinus Thrombosis ◽

Cerebral Venous Sinus Thrombosis ◽

Venous Sinus ◽

Nonconvulsive Status Epilepticus ◽

Diagnostic Investigation ◽

Venous Sinus Thrombosis ◽

Psychiatric Syndrome

ABSTRACT Although catatonia is a well-known psychiatric syndrome, there are many possible systemic and neurological etiologies. The aim of this case report was to present a case of a patient with cerebral venous sinus thrombosis and infarction in which catatonia was the clinical manifestation of a possible nonconvulsive status epilepticus. To our knowledge, only one such case has been reported in the literature, which had a simplified diagnostic investigation. It is important to correctly recognize the organic cause underlying catatonia in order to treat the patient as soon as possible thereby improving outcome. Therefore, physicians need to update their knowledge on catatonia, recognizing that it can be part of a psychiatric or neurologic condition.

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