Nonconvulsive Status Epilepticus in the Elderly: A Case Series and a Review of the Literature

1998 ◽  
Vol 11 (2) ◽  
pp. 74-78 ◽  
Author(s):  
Douglas Labar ◽  
Juan Barrera ◽  
Gail Solomon ◽  
Cynthia Harden
2011 ◽  
Vol 5 (1) ◽  
pp. 15-25
Author(s):  
Rocco Galimi

In the elderly, new onset of epilepsy is often associated with vague complaints such as confusion, altered mental status, or memory problems. The absence of clinically apparent convulsions in association with an electroencephalogram showing continuous or recurrent seizure activity has been called nonconvulsive status epilepticus (NCSE). The purpose of this article is to describe the clinical and electroencephalographic features of NCSE in older adults. NCSE is an important, under-recognised and reversible cause of acute prolonged confusion. Although attempts have been made to define and classify this disorder, there is no universally accepted definition or classification yet that encompasses all subtypes or electroclinical scenarios. A urgent electroencephalogram is considered as the method of choice in the diagnostic evaluation of NCSE. Further researches are needed to better define NCSE.


2020 ◽  
Vol 176 (9) ◽  
pp. 701-709
Author(s):  
S. Dupont ◽  
K. Kinugawa

2015 ◽  
Vol 3 ◽  
pp. 8-11 ◽  
Author(s):  
Go Taniguchi ◽  
Miho Miyajima ◽  
Masako Watanabe ◽  
Yoshiko Murata ◽  
Daichi Sone ◽  
...  

Author(s):  
Alberto M. Cappellari ◽  
Donata Rossetti ◽  
Sabrina Avignone ◽  
Elisa Scola ◽  
Antonio Di Cesare

AbstractMetronidazole-induced encephalopathy is a rare toxic encephalopathy secondary to the common use to this antimicrobial drug. It has been reported mainly in adult patients but only rarely in children. Owing to possible devastating complication of this disease, clinicians should have a higher index of suspicion for encephalopathic patients on metronidazole therapy. Here, we report a 5-month-old infant with metronidazole-induced encephalopathy presenting with nonconvulsive status epilepticus. A review of the literature in pediatric, as well as adult metronidazole-induced encephalopathy, is also provided.


2018 ◽  
Vol 9 (2) ◽  
pp. 100-104 ◽  
Author(s):  
Dmitry Tchapyjnikov ◽  
Matthew W. Luedke

Cefepime is a fourth-generation cephalosporin antibiotic known to have neurotoxic side effects. Recent reports have described patients on cefepime presenting with altered mentation and concurrent triphasic wave discharges on electroencephalogram (EEG). Some have described this clinical presentation as cefepime-induced encephalopathy, while others have termed it as cefepime-induced nonconvulsive status epilepticus (NCSE). We report on 4 patients who developed cefepime-associated altered mentation with triphasic discharges on EEG. A benzodiazepine trial was attempted in 3 of the patients, all of whom had improvement in the frequency of the triphasic discharges, but only 2 of whom demonstrated a concurrent partial and transient improvement in mental status. All 4 patients had normalization of mental status upon discontinuation of cefepime. We provide a literature review of prior cases and propose that these reports, including those labeled as NCSE, are best described as a cefepime-induced encephalopathy with triphasic discharges as opposed to an ictal phenomenon. We contend that aggressive treatment with anti-seizure medications is not warranted and that cefepime discontinuation is the definitive treatment. This case series and review of the literature clarifies a long-standing terminological ambiguity in a unique clinical picture that can be encountered by the neurohospitalist or other providers.


Epilepsia ◽  
2007 ◽  
Vol 48 (5) ◽  
pp. 966-972 ◽  
Author(s):  
F.J. Bottaro ◽  
O.A. Martinez ◽  
M.M. Fernandez Pardal ◽  
J.E. Bruetman ◽  
R.C. Reisin

2018 ◽  
Vol 79 ◽  
pp. 53-57 ◽  
Author(s):  
Nuno Canas ◽  
Henrique Delgado ◽  
Vanessa Silva ◽  
Ana Rita Pinto ◽  
Sandra Sousa ◽  
...  

2004 ◽  
Vol 52 (3) ◽  
pp. 476-477 ◽  
Author(s):  
Yann Martin ◽  
Marie-Agnes Artaz ◽  
Anne Bornand-Rousselot

2020 ◽  
Vol 03 (01) ◽  
Author(s):  
Soufiane Aharram ◽  
Jawad Amghar ◽  
Mounir Yahyaoui ◽  
Omar Agoumi ◽  
Abdelkarim Daoudi

2012 ◽  
Vol 171 (10) ◽  
pp. 1541-1547 ◽  
Author(s):  
Guido F. Weißhaar ◽  
Marc Hoemberg ◽  
Katja Bender ◽  
Ursula Bangen ◽  
Peter Herkenrath ◽  
...  

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