Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: An 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients

2009 ◽  
Vol 31 (12) ◽  
pp. 2860-2872 ◽  
Author(s):  
Jinhyun Kim ◽  
Eun Young Lee ◽  
Eun-Mi Koh ◽  
Hoon-Suk Cha ◽  
Bin Yoo ◽  
...  
1976 ◽  
Vol 4 (3) ◽  
pp. 179-182 ◽  
Author(s):  
D M Lomas ◽  
J Gay ◽  
R N Midha ◽  
D L Postlethwaite

Three hundred and twelve patients suffering from painful conditions were admitted to a multicentre, double-blind controlled trial, conducted in general practice in which five analgesics—floctafenine (Idarac), paracetamol, aspirin, dihydrocodeine and pentazocine—were compared. Overall ratings of analgesic effect placed floctafenine first in rank order. Floctafenine was statistically significantly superior in effect to pentazocine but not to the other three agents as far as doctor ratings were concerned; and superior to both pentazocine and dihydrocodeine in the opinion of patients. Fewer patients experienced side-effects on floctafenine than on the other four analgesics and this difference between floctafenine and pentazocine, and floctafenine and dihydrocodeine was statistically significant.


10.19082/7489 ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 7489-7498
Author(s):  
Ali Ansari Jaberi ◽  
Tahere Norouzi ◽  
Shahin Haydari ◽  
Tayebeh Negahban Bonabi

2020 ◽  
Vol 34 (8) ◽  
pp. 2067-2073 ◽  
Author(s):  
Motahar Heidari‐Beni ◽  
Amir R. Moravejolahkami ◽  
Pegah Gorgian ◽  
Gholamreza Askari ◽  
Mohammad J. Tarrahi ◽  
...  

1975 ◽  
Vol 3 (4) ◽  
pp. 251-260 ◽  
Author(s):  
J E Murphy

A double-blind controlled comparative clinical trial of Org GB 94 and imipramine was conducted in general practice. Fifty-five patients were treated with Org GB 94 (60 mg daily) and fifty-four with imipramine (150 mg daily). In the doses employed both agents were equally effective in relieving depression over a four week treatment period. Tolerance of the two agents was similar. Although no statistically significant differences emerged, with regard to both therapeutic effect and some side-effects a trend in favour of Org GB 94 was apparent.


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