Antimelanogenic activity of a novel adamantyl benzylbenzamide derivative, AP736: a randomized, double-blind, vehicle-controlled comparative clinical trial performed in patients with hyperpigmentation during the summer

2015 ◽  
Vol 55 (6) ◽  
pp. e321-e326 ◽  
Author(s):  
Yeon Su Jeong ◽  
Jeong-Hwan Kim ◽  
Joonho Choi ◽  
Heung Soo Baek ◽  
Yung Hyup Joo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Double Blind ◽  
Comparative Clinical Trial

A Double-Blind Comparative Clinical Trial of Floctafenine and Four Other Analgesics Conducted in General Practice

1976 ◽  
Vol 4 (3) ◽  
pp. 179-182 ◽  
Author(s):  
D M Lomas ◽  
J Gay ◽  
R N Midha ◽  
D L Postlethwaite
Keyword(s):  
Clinical Trial ◽  
General Practice ◽  
Side Effects ◽  
Analgesic Effect ◽  
Rank Order ◽  
Controlled Trial ◽  
The Other ◽  
Double Blind ◽  
Comparative Clinical Trial

Three hundred and twelve patients suffering from painful conditions were admitted to a multicentre, double-blind controlled trial, conducted in general practice in which five analgesics—floctafenine (Idarac), paracetamol, aspirin, dihydrocodeine and pentazocine—were compared. Overall ratings of analgesic effect placed floctafenine first in rank order. Floctafenine was statistically significantly superior in effect to pentazocine but not to the other three agents as far as doctor ratings were concerned; and superior to both pentazocine and dihydrocodeine in the opinion of patients. Fewer patients experienced side-effects on floctafenine than on the other four analgesics and this difference between floctafenine and pentazocine, and floctafenine and dihydrocodeine was statistically significant.

A Comparative Clinical Trial of Org GB 94 and Imipramine in the Treatment of Depression in General Practice

1975 ◽  
Vol 3 (4) ◽  
pp. 251-260 ◽  
Author(s):  
J E Murphy
Keyword(s):  
Clinical Trial ◽  
General Practice ◽  
Side Effects ◽  
Treatment Period ◽  
Therapeutic Effect ◽  
Double Blind ◽  
Comparative Clinical Trial ◽  
Two Agents ◽  
Treatment Of Depression

A double-blind controlled comparative clinical trial of Org GB 94 and imipramine was conducted in general practice. Fifty-five patients were treated with Org GB 94 (60 mg daily) and fifty-four with imipramine (150 mg daily). In the doses employed both agents were equally effective in relieving depression over a four week treatment period. Tolerance of the two agents was similar. Although no statistically significant differences emerged, with regard to both therapeutic effect and some side-effects a trend in favour of Org GB 94 was apparent.

A Comparative Clinical Trial of Diflunisal and Ibuprofen in the Control of Pain in Osteoarthritis

1979 ◽  
Vol 7 (4) ◽  
pp. 272-276 ◽  
Author(s):  
J G M Keet
Keyword(s):  
Clinical Trial ◽  
Blind Study ◽  
Double Blind Study ◽  
Efficacy And Safety ◽  
Double Blind ◽  
Comparative Clinical Trial ◽  
Treatment Groups ◽  
Ambulatory Patients ◽  
Efficacy Parameters ◽  
Osteoarthritis Of Hip

A randomized double-blind study in ambulatory patients with osteoarthritis of hip and/or knee was conducted, comparing the efficacy and safety of diflunisal 500 mg daily with ibuprofen 1200 mg daily, over a period of 8 weeks. Thirty-five patients participated in the study. The results revealed no significant differences between the treatment groups with regard to the efficacy parameters.

A Comparative Clinical Trial of Benorylate and Indomethacin in the Treatment of Active Rheumatoid Arthritis in General Practice

1974 ◽  
Vol 2 (1) ◽  
pp. 66-70 ◽  
Author(s):  
Alastair Malcolm
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trial ◽  
General Practice ◽  
Active Rheumatoid Arthritis ◽  
Double Blind ◽  
Comparative Clinical Trial

Benorylate was compared with indomethacin in a double-blind cross-over trial in patients with rheumatoid arthritis. Twelve patients completed treatment. All measurements showed a trend towards benorylate giving greater improvement, although the differences were not statistically significant. Nine patients out of the twelve preferred benorylate.

Flutrimazole 1% dermal cream in the treatment of dermatomycoses: a randomized, multicentre, double-blind, comparative clinical trial with 1% clotrimazole cream

Mycoses ◽  
1994 ◽  
Vol 37 (11-12) ◽  
pp. 455-459 ◽  
Author(s):  
O. Binet ◽  
J. Soto-Melo ◽  
J. Delgadillo ◽  
S. Videla ◽  
I. Izquierdo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Double Blind ◽  
Comparative Clinical Trial
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