Fed and Fasted Single-dose Assessment of Bioequivalence of Dapagliflozin and Metformin Extended-release Fixed-dose Combination Tablets Relative to Single-component Dapagliflozin and Metformin Extended-release Tablets in Healthy Subjects

David W. Boulton; Ming Chang; Steven C. Griffen; Catia Kitaura; Susan Lubin; Allyson Pollack; Frank LaCreta

doi:10.1016/j.clinthera.2015.11.010

Fed and Fasted Single-dose Assessment of Bioequivalence of Dapagliflozin and Metformin Extended-release Fixed-dose Combination Tablets Relative to Single-component Dapagliflozin and Metformin Extended-release Tablets in Healthy Subjects

Clinical Therapeutics ◽

10.1016/j.clinthera.2015.11.010 ◽

2016 ◽

Vol 38 (1) ◽

pp. 99-109 ◽

Cited By ~ 9

Author(s):

David W. Boulton ◽

Ming Chang ◽

Steven C. Griffen ◽

Catia Kitaura ◽

Susan Lubin ◽

...

Keyword(s):

Single Dose ◽

Healthy Subjects ◽

Extended Release ◽

Single Component ◽

Dose Assessment ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Bioequivalence, Food Effect, and Steady‐State Assessment of Dapagliflozin/Metformin Extended‐release Fixed‐dose Combination Tablets Relative to Single‐component Dapagliflozin and Metformin Extended‐release Tablets in Healthy Subjects

Clinical Therapeutics ◽

10.1016/j.clinthera.2015.05.004 ◽

2015 ◽

Vol 37 (7) ◽

pp. 1517-1528 ◽

Cited By ~ 9

Author(s):

Ming Chang ◽

Xiaoni Liu ◽

Dapeng Cui ◽

Dan Liang ◽

Frank LaCreta ◽

...

Keyword(s):

Steady State ◽

Healthy Subjects ◽

Extended Release ◽

Food Effect ◽

State Assessment ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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P3-391: PHARMACOKINETICS OF MEMANTINE AND DONEPEZIL AFTER A SINGLE DOSE OF A ONCE-DAILY FIXED-DOSE COMBINATION CAPSULE OF MEMANTINE EXTENDED RELEASE AND DONEPEZIL IN TWO PHASE I TRIALS

Alzheimer s & Dementia ◽

10.1016/j.jalz.2014.05.1485 ◽

2014 ◽

Vol 10 ◽

pp. P772-P773

Author(s):

Ramesh Boinpally ◽

Robert Hofbauer ◽

Laishun Chen ◽

Stephen Zukin ◽

Antonia Periclou

Keyword(s):

Single Dose ◽

Phase I ◽

Extended Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Phase I Trials ◽

Two Phase ◽

Once Daily ◽

Dose Combination

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Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects

Drug Design Development and Therapy ◽

10.2147/dddt.s102459 ◽

2016 ◽

pp. 1411 ◽

Cited By ~ 1

Author(s):

Kyung-Sang Yu ◽

Su-jin Rhee ◽

Seung Hwan Lee ◽

Seo Hyun Yoon ◽

Joo-Youn Cho ◽

...

Keyword(s):

Healthy Subjects ◽

Extended Release ◽

Food Effect ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination ◽

Combination Formulation

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Bioequivalence of Saxagliptin/Metformin Extended-Release (XR) Fixed-Dose Combination Tablets and Single-Component Saxagliptin and Metformin XR Tablets in Healthy Adult Chinese Subjects

Clinical Drug Investigation ◽

10.1007/s40261-014-0230-1 ◽

2014 ◽

Vol 34 (11) ◽

pp. 763-772 ◽

Cited By ~ 3

Author(s):

Anders Gummesson ◽

Haiyan Li ◽

Michael Gillen ◽

John Xu ◽

Mohammad Niazi ◽

...

Keyword(s):

Extended Release ◽

Healthy Adult ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination ◽

Chinese Subjects

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The Pharmacokinetics and Safety of a Fixed-Dose Combination of Acetylsalicylic Acid and Clopidogrel Compared With the Concurrent Administration of Acetylsalicylic Acid and Clopidogrel in Healthy Subjects: A Randomized, Open-Label, 2-Sequence, 2-Period, Single-Dose Crossover Study

Clinical Therapeutics ◽

10.1016/j.clinthera.2013.05.015 ◽

2013 ◽

Vol 35 (7) ◽

pp. 985-994 ◽

Cited By ~ 8

Author(s):

Jin Ah Jung ◽

Tae-Eun Kim ◽

Jung-Ryul Kim ◽

Min-Ji Kim ◽

Wooseong Huh ◽

...

Keyword(s):

Single Dose ◽

Acetylsalicylic Acid ◽

Crossover Study ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Concurrent Administration ◽

Open Label ◽

Dose Combination

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Bioequivalence of macitentan and tadalafil given as fixed‐dose combination or single‐component tablets in healthy subjects

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14347 ◽

2020 ◽

Vol 86 (12) ◽

pp. 2424-2434

Author(s):

Simon Grill ◽

Shirin Bruderer ◽

Patricia N. Sidharta ◽

Mariya Antonova ◽

Susanne Globig ◽

...

Keyword(s):

Healthy Subjects ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Bioequivalence of Saxagliptin/Metformin Extended-Release (XR) Fixed-Dose Combination Tablets and Single-Component Saxagliptin and Metformin XR Tablets in Healthy Adult Subjects

Clinical Drug Investigation ◽

10.2165/11590290-000000000-00000 ◽

2011 ◽

Vol 31 (9) ◽

pp. 619-630 ◽

Cited By ~ 16

Author(s):

David W. Boulton ◽

Charles H. Smith ◽

L. Li ◽

Jian Huang ◽

Angela Tang ◽

...

Keyword(s):

Extended Release ◽

Healthy Adult ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Single-Pill Triple Fixed Dose Combination Therapy with Single Component Drug Monitoring in Treatment-Resistant Hypertension: A Pilot Study

Current Vascular Pharmacology ◽

10.2174/1570161115666170821155555 ◽

2018 ◽

Vol 16 (2) ◽

pp. 197-203 ◽

Cited By ~ 1

Author(s):

Reinhold Kreutz ◽

Jurgen Scholze ◽

Antonios Douros

Keyword(s):

Pilot Study ◽

Combination Therapy ◽

Drug Monitoring ◽

Resistant Hypertension ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Treatment Resistant ◽

Single Pill ◽

Dose Combination

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Effect of food on the oral bioavailability of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide fixed dose combination tablets in healthy subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.131 ◽

2014 ◽

Vol 3 (6) ◽

pp. 487-492 ◽

Cited By ~ 3

Author(s):

Gangadhar Sunkara ◽

Xuemin Jiang ◽

Christine Reynolds ◽

Denise Serra ◽

Yiming Zhang ◽

...

Keyword(s):

Oral Bioavailability ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Effect Of Food ◽

Dose Combination

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Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Journal of Korean Medical Science ◽

10.3346/jkms.2018.33.e258 ◽

2018 ◽

Vol 33 (41) ◽

Author(s):

Yong-Soon Cho ◽

Shi Hyang Lee ◽

Hyeong-Seok Lim ◽

Kyun-Seop Bae

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Individual Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

High Dose ◽

Combination Tablet ◽

Dose Combination

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