Improved mortality with the implementation of an MDT to determine patient selection for percutaneous endoscopic gastrostomy (PEG) insertion–A retrospective audit; single centre experience

Background: Peritoneal dialysis (PD) is the preferred dialysis modality for paediatric patients with end-stage kidney disease. Frequently, malnutrition is encountered. Percutaneous endoscopic gastrostomy (PEG) is the preferred mode of feeding because of its minimal invasive mode of placement and easy handling in daily life. However, reports of a high risk for early post-interventional peritonitis hampered this procedure during PD and controlled studies on the benefit of peri-interventional management to prevent peritonitis are lacking. Here, we report the safety profile of PEG insertion among a cohort of children on PD by using a prophylactic antibiotic and antifungal regimen as well as modification of the PD programme. Methods: We performed a single-centre analysis of paediatric PD patients receiving PEG placement between 2015 and 2020. Demographic data, peri-interventional prophylactic antibiotic and antifungal treatment as well as modification of the PD programme were gathered and the incidence of peritonitis within a period of 28 days after PEG was calculated. Results: Eight PD patients (median weight 6.7 kg) received PEG insertion. Antibiotic and antifungal prophylaxis were prescribed for median time of 4.0 and 5.0 days, respectively. After individual reduction of PD intensity, all patients continued their regular PD programme after a median of 6 days. One patient developed peritonitis within 24 h after PEG insertion and simultaneous surgery for hydrocele. Conclusions: Applying an antibiotic and antifungal prophylactic regime as well as an adapted PD programme may reduce the risk for peritonitis in paediatric PD patients who receive PEG procedure.

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Single-Centre Experience with Patients Selection for Mechanical Thrombectomy Based on Automated Computed Tomography Perfusion Analysis–A Comparison with Computed TomographyCT Perfusion Thrombectomy Trials

Journal of Stroke and Cerebrovascular Diseases ◽

10.1016/j.jstrokecerebrovasdis.2018.12.041 ◽

2019 ◽

Vol 28 (4) ◽

pp. 1085-1092 ◽

Cited By ~ 2

Author(s):

Jiri Vanicek ◽

Petra Cimflova ◽

Martin Bulik ◽

Jiri Jarkovsky ◽

Veronika Prelecova ◽

...

Keyword(s):

Computed Tomography ◽

Mechanical Thrombectomy ◽

Single Centre ◽

Computed Tomography Perfusion ◽

Single Centre Experience ◽

Selection For

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146 Retrospective audit of treatment outcomes from palliative thoracic radiotherapy – a single centre experience

Lung Cancer ◽

10.1016/s0169-5002(16)30163-5 ◽

2016 ◽

Vol 91 ◽

pp. S53

Author(s):

Z. Aladili ◽

D.J. Kearns ◽

O. Chan

Keyword(s):

Treatment Outcomes ◽

Thoracic Radiotherapy ◽

Single Centre ◽

Retrospective Audit ◽

Single Centre Experience

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Risk factors for patient selection in ambulatory laparoscopic cholecystectomy: A Single-centre experience

Journal of Minimal Access Surgery ◽

10.4103/jmas.jmas_25_21 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

Jingcheng Hao ◽

Qiang Wu ◽

Ning Fu ◽

Weiwei Chen ◽

Xueli Jin ◽

...

Keyword(s):

Risk Factors ◽

Laparoscopic Cholecystectomy ◽

Patient Selection ◽

Single Centre ◽

Single Centre Experience

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Percutaneous endoscopic gastrostomy and gastrojejunostomy: a critical reappraisal of patient selection, tube function and the feasibility of nutritional support during extended follow-up

Gastrointestinal Endoscopy ◽

10.1016/s0016-5107(99)70153-7 ◽

1999 ◽

Vol 50 (6) ◽

pp. 746-754 ◽

Cited By ~ 58

Author(s):

Lisbeth M.H. Mathus-Vliegen ◽

Hanna Koning

Keyword(s):

Percutaneous Endoscopic Gastrostomy ◽

Patient Selection ◽

Nutritional Support ◽

Endoscopic Gastrostomy ◽

Tube Function

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499 A Retrospective Audit on Detection Rate of Clinically Significant Cancer Among MP-MRI Targeted Biopsy – A Single Centre Experience

British Journal of Surgery ◽

10.1093/bjs/znab259.059 ◽

2021 ◽

Vol 108 (Supplement_6) ◽

Author(s):

E T Zuling ◽

S Murali-Krishnan

Keyword(s):

Detection Rate ◽

Specific Antigen ◽

Transrectal Ultrasound ◽

High Serum ◽

Targeted Biopsy ◽

Single Centre ◽

Trus Biopsy ◽

Retrospective Audit ◽

Single Centre Experience ◽

Clinically Significant

Abstract Men with high serum prostate specific antigen (PSA) typically undergo standard transrectal ultrasound-guided prostate biopsy (TRUS-biopsy) during which 10 to 12 cores are obtained. TRUS-biopsy can cause side-effects including bleeding, pain, and infection. Multi-parametric MRI (MP-MRI) used as a triage test might allow men to avoid unnecessary TRUS-biopsy and improve diagnostic accuracy. According to the renowned PROMIS study, for clinically significant cancer, MP-MRI was more sensitive and less specific than TRUS-biopsy. In this study, we performed a single centre, retrospective audit on the detection rate of clinically significant cancer among MP-MRI targeted biopsy and compare it with the standard TRUS biopsy. Clinically significant cancer is defined as Gleason score ³ 4 +3 or a maximum cancer core length 6mm or longer. Besides, we also compare the rate of clinically significant cancer in MP-MRI targeted biopsy against the PROMIS study. Through this audit, we found that in 2019, there is a 54% (60 out of 112 patients) of clinically significant cancer in MP-MRI biopsy and 41% (26 out of 64 patients) of clinically significant cancer among standard TRUS biopsy. Comparing it with the PROMIS study in which clinically significant cancer was detected in 38% in the MP-MRI targeted biopsy group and 26% in the standard-biopsy group, the adjusted difference in our study (13%) is similar to PROMIS study which is 12%. In conclusion, our study reaffirms that MP-MRI targeted biopsy reduce over-diagnosis of clinically insignificant prostate cancer and improve detection of clinically significant cancer.

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