AbstractThis study considers structural optimization under a reliability constraint, in which the input distribution is only partially known. Specifically, when it is only known that the expected value vector and the variance-covariance matrix of the input distribution belong to a given convex set, it is required that the failure probability of a structure should be no greater than a specified target value for any realization of the input distribution. We demonstrate that this distributionally-robust reliability constraint can be reduced equivalently to deterministic constraints. By using this reduction, we can handle a reliability-based design optimization problem under the distributionally-robust reliability constraint within the framework of deterministic optimization; in particular, nonlinear semidefinite programming. Two numerical examples are solved to demonstrate the relation between the optimal value and either the target reliability or the uncertainty magnitude.