scholarly journals Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: Implications for oxygen sensing and hypoxic signaling in eukaryotes

2006 ◽  
Vol 3 (4) ◽  
pp. 277-287 ◽  
Author(s):  
Pablo R. Castello ◽  
Pamela S. David ◽  
Travis McClure ◽  
Zachary Crook ◽  
Robert O. Poyton
Keyword(s):  
Nitric Oxide ◽  
Cytochrome Oxidase ◽  
Oxygen Sensing ◽  
Mitochondrial Cytochrome ◽  
Hypoxic Conditions ◽  
Mitochondrial Cytochrome Oxidase

Nitric oxide, hypoxia and brain inflammation

2004 ◽  
Vol 32 (6) ◽  
pp. 1068-1069 ◽  
Author(s):  
P. Mander ◽  
G.C. Brown
Keyword(s):  
Nitric Oxide ◽  
Cytochrome Oxidase ◽  
Brain Inflammation ◽  
Mitochondrial Cytochrome ◽  
No Donor ◽  
Ischaemic Damage ◽  
Oxide Synthase ◽  
The Brain ◽  
Mitochondrial Cytochrome Oxidase ◽  
Inducible Nos

NO (nitric oxide) acutely and potently inhibits mitochondrial cytochrome oxidase in competition with oxygen, thereby raising the apparent KM for oxygen of mitochondria and neurons into the physiological or pathological range. We find that NO from an NO donor or glial inducible NOS (nitric oxide synthase) highly sensitizes neurons to hypoxia-induced death, probably via the NO–oxygen competition at cytochrome oxidase. Thus the NO from neuronal NOS during excitotoxicity or the NO from inducible NOS during inflammation may sensitize the brain to hypoxic/ischaemic damage.

First rearing record and DNA sequence of Chromatomyia aizoon (Hering, 1932) (Diptera: Agromyzidae) associated with Saxifraga paniculata Miller from the Czech Republic

2020 ◽  
Vol 69 (3) ◽  
pp. 283-288
Author(s):  
Miloš Černý ◽  
Jiří Kocián ◽  
Jan Ševčík
Keyword(s):  
Czech Republic ◽  
Cytochrome Oxidase ◽  
Dna Sequence ◽  
Partial Sequence ◽  
Mitochondrial Cytochrome ◽  
Cytochrome Oxidase Subunit ◽  
Cytochrome Oxidase Subunit I ◽  
Mitochondrial Cytochrome Oxidase Subunit ◽  
The Czech Republic ◽  
Mitochondrial Cytochrome Oxidase

Abstract A male of Chromatomyia aizoon (Hering, 1932) (Diptera: Agromyzidae) was reared from a leaf mine at Saxifraga paniculata collected in Štramberk (Northern Moravia, Czech Republic). Partial sequence of the mitochondrial cytochrome oxidase subunit I (COI barcode region, 658 bp) is also provided.

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