Discovery of novel and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B): Virtual screening and molecular dynamic simulation

Tyrosine Phosphatase ◽

Selective Inhibitors ◽

Exploring the cause of the inhibitor 4AX attaching to binding site disrupting protein tyrosine phosphatase 4A1 trimerization by molecular dynamic simulation

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2019.1567392 ◽

2019 ◽

Vol 37 (18) ◽

pp. 4840-4851 ◽

Cited By ~ 3

Author(s):

Li Wei-Ya ◽

Duan Yu-Qing ◽

Ma Yang-Chun ◽

Lu Xin-Hua ◽

Ma Ying ◽

...

Keyword(s):

Molecular Dynamic Simulation ◽

Binding Site ◽

Molecular Dynamic ◽

Dynamic Simulation ◽

Tyrosine Phosphatase ◽

Virtual Screening of Novel and Selective Inhibitors of Protein Tyrosine Phosphatase 1B over T-Cell Protein Tyrosine Phosphatase Using a Bidentate Inhibition Strategy

Journal of Chemical Information and Modeling ◽

10.1021/acs.jcim.8b00040 ◽

2018 ◽

Vol 58 (4) ◽

pp. 837-847 ◽

Cited By ~ 6

Author(s):

Xi Chen ◽

Qiang Gan ◽

Changgen Feng ◽

Xia Liu ◽

Qian Zhang

Keyword(s):

T Cell ◽

Virtual Screening ◽

Tyrosine Phosphatase ◽

Cell Protein ◽

Selective Inhibitors ◽

Diphenylether Derivative as Selective Inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) Over T-cell Protein Tyrosine Phosphatase (TCPTP) Identified through Virtual Screening

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557511313110006 ◽

2013 ◽

Vol 13 (11) ◽

pp. 1602-1606 ◽

Cited By ~ 6

Author(s):

M. Reddy ◽

Chakshusmathi Ghadiyaram ◽

Sunil Panigrahi ◽

Subramanya Hosahalli ◽

Lakshmi Mangamoori

Keyword(s):

T Cell ◽

Virtual Screening ◽

Tyrosine Phosphatase ◽

Selective Inhibitor ◽

Cell Protein ◽

Molecular docking and virtual screening for novel protein tyrosine phosphatase 1B (PTP1B) inhibitors

Bioinformation ◽

10.6026/97320630008834 ◽

2012 ◽

Vol 8 (17) ◽

pp. 834-837 ◽

Cited By ~ 5

Author(s):

Pasupuleti Sreenivasa Rao

Keyword(s):

Molecular Docking ◽

Virtual Screening ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Ptp1b Inhibitors ◽

Novel Protein

Discovery of inhibitors targeting protein tyrosine phosphatase 1B using a combined virtual screening approach

Molecular Diversity ◽

10.1007/s11030-021-10323-2 ◽

2021 ◽

Author(s):

Dan Zhao ◽

Lu Sun ◽

Shijun Zhong

Keyword(s):

Virtual Screening ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Screening Approach ◽

Virtual Screening Approach

Formylchromone derivatives as irreversible and selective inhibitors of human protein tyrosine phosphatase 1B. Kinetic and modeling studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2004.11.006 ◽

2005 ◽

Vol 13 (4) ◽

pp. 1325-1332 ◽

Cited By ~ 27

Author(s):

Yi Sup Shim ◽

Ki Chul Kim ◽

Kyung A. Lee ◽

Suja Shrestha ◽

Keun-Hyeung Lee ◽

...

Keyword(s):

Tyrosine Phosphatase ◽

Human Protein ◽

Selective Inhibitors ◽

Protein Tyrosine ◽

Modeling Studies

Potent, selective inhibitors of protein tyrosine phosphatase 1B

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(03)00302-0 ◽

2003 ◽

Vol 13 (11) ◽

pp. 1887-1890 ◽

Cited By ~ 34

Author(s):

Zhili Xin ◽

Thorsten K Oost ◽

Cele Abad-Zapatero ◽

Philip J Hajduk ◽

Zhonghua Pei ◽

...

Keyword(s):

Tyrosine Phosphatase ◽

Selective Inhibitors ◽

Design and Synthesis of Imidazolidine-2,4-Dione Derivatives as Selective Inhibitors by Targeting Protein Tyrosine Phosphatase-1B Over T-Cell Protein Tyrosine Phosphatase

Chemical Biology & Drug Design ◽

10.1111/cbdd.12189 ◽

2013 ◽

Vol 82 (5) ◽

pp. 595-602 ◽

Cited By ~ 4

Author(s):

Ying Ma ◽

Su-Xia Sun ◽

Xian-Chao Cheng ◽

Shu-Qing Wang ◽

Wei-Li Dong ◽

...

Keyword(s):

T Cell ◽

Tyrosine Phosphatase ◽

Cell Protein ◽

Selective Inhibitors ◽

Protein Tyrosine ◽

Design And Synthesis

Potent, Selective Inhibitors of Protein Tyrosine Phosphatase 1B.

ChemInform ◽

10.1002/chin.200336158 ◽

2003 ◽

Vol 34 (36) ◽

Author(s):

Zhili Xin ◽

et al. et al.

Keyword(s):

Tyrosine Phosphatase ◽

Selective Inhibitors ◽

Combined Ligand- and Receptor-Based Virtual Screening Methodology to Identify Structurally Diverse Protein Tyrosine Phosphatase 1B Inhibitors

ChemMedChem ◽

10.1002/cmdc.201800267 ◽

2018 ◽

Vol 13 (18) ◽

pp. 1939-1948 ◽

Cited By ~ 1

Author(s):

Aleix Gimeno ◽

Andrea Ardid-Ruiz ◽

María José Ojeda-Montes ◽

Sarah Tomás-Hernández ◽

Adrià Cereto-Massagué ◽

...

Keyword(s):

Virtual Screening ◽

Tyrosine Phosphatase ◽