scholarly journals Associations between patient-reported outcomes and radiation dose in patients treated with radiation therapy for primary brain tumours

2021 ◽  
Vol 31 ◽  
pp. 86-92
Author(s):  
L. Haldbo-Classen ◽  
A. Amidi ◽  
L.M. Wu ◽  
S. Lukacova ◽  
G. Oettingen ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Radiation Dose ◽  
Brain Tumours ◽  
Patient Reported Outcomes ◽  
Primary Brain Tumours ◽  
Patient Reported

scholarly journals Analysis of Radiation Dose to the Shoulder by Treatment Technique and Correlation With Patient Reported Outcomes in Patients Receiving Regional Nodal Irradiation

2021 ◽  
Vol 11 ◽  
Author(s):  
Jose G. Bazan ◽  
Dominic DiCostanzo ◽  
Karen Hock ◽  
Sachin Jhawar ◽  
Karla Kuhn ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiation Therapy ◽  
Radiation Dose ◽  
Patient Reported Outcomes ◽  
Late Complication ◽  
Treatment Technique ◽  
Regional Nodal Irradiation ◽  
Patient Reported ◽  
The Impact ◽  
Dash Questionnaire

Background/PurposeShoulder/arm morbidity is a late complication of breast cancer treatment with surgery and regional nodal irradiation (RNI). We set to analyze the impact of radiation technique [intensity modulated radiation therapy (IMRT) or 3D conformal radiation therapy (3DCRT)] on radiation dose to the shoulder with a hypothesis that IMRT use results in smaller volume of shoulder receiving radiation. We explored the relationship of treatment technique on long-term patient-reported outcomes using the quick disabilities of the arm, shoulder, and hand (q-DASH) questionnaire.Materials/MethodsWe identified patients treated with adjuvant RNI (50 Gy/25 fractions) from 2013 to 2018. We retrospectively contoured the shoulder organ-at-risk (OAR) from 2 cm above the ipsilateral supraclavicular (SCL) planning target volume (PTV) to the inferior SCL PTV slice and calculated the absolute volume of shoulder OAR receiving 5–50 Gy (V5–V50). We identified patients that completed a q-DASH questionnaire ≥6 months from the end of RNI.ResultsWe included 410 RNI patients: 54% stage III, 72% mastectomy, 35% treated with IMRT. IMRT resulted in significant reductions in the shoulder OAR volume receiving 20–50 Gy vs. 3DCRT. In total, 82 patients completed the q-DASH. The mean (SD) q-DASH=25.4 (19.1) and tended to be lower with IMRT vs. 3DCRT: 19.6 (16.4) vs. 27.8 (19.8), p=0.078.ConclusionWe found that IMRT reduces radiation dose to the shoulder and is associated with a trend toward reduced q-DASH scores ≥6 months post-RNI in a subset of our cohort. These results support prospective evaluation of IMRT as a technique to reduce shoulder morbidity in breast cancer patients receiving RNI.

scholarly journals P05.53 Long-term cognitive function after radiation therapy for primary brain tumours grade I-III

2018 ◽  
Vol 20 (suppl_3) ◽  
pp. iii315-iii315
Author(s):  
L Haldbo-Classen ◽  
A Amidi ◽  
S Lukacova ◽  
L Wu ◽  
G von Oettingen ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Cognitive Function ◽  
Brain Tumours ◽  
Primary Brain Tumours

scholarly journals Patient-reported outcomes after prostate only vs. prostate and pelvic lymph node radiation therapy

2020 ◽  
Vol 19 ◽  
pp. e2134
Author(s):  
M.G. Parry ◽  
J. Nossiter ◽  
T.E. Cowling ◽  
A. Sujenthiran ◽  
B. Berry ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Lymph Node ◽  
Patient Reported Outcomes ◽  
Pelvic Lymph Node ◽  
Patient Reported
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