Mycophenolate mofetil treatment in patients with autoimmune hepatitis failing standard therapy with prednisolone and azathioprine

2019 ◽  
Vol 51 (2) ◽  
pp. 253-257 ◽  
Author(s):  
Georgios Giannakopoulos ◽  
Hans Verbaan ◽  
Inga-Lill Friis-Liby ◽  
Per Sangfelt ◽  
Nils Nyhlin ◽  
...  
2004 ◽  
Vol 18 (5) ◽  
pp. 321-326 ◽  
Author(s):  
Shane M Devlin ◽  
Mark G Swain ◽  
Stefan J Urbanski ◽  
Kelly W Burak

There are limited therapeutic options available for patients with autoimmune hepatitis in whom conventional treatment fails. A case series of five patients unresponsive to or unable to take azathioprine, 6-mercaptopurine or corticosteroids who were treated with mycophenolate mofetil (MMF) is reported. While on MMF, alanine aminotransferase normalized or remained normal in all patients. MMF had a steroid-sparing effect and histological remission was demonstrated in one patient after seven months of MMF. One patient experienced an uncomplicated episode of pyelonephritis. In conclusion, MMF can effectively induce and maintain remission in refractory autoimmune hepatitis patients.


2018 ◽  
Vol 16 (2) ◽  
pp. 268-277 ◽  
Author(s):  
Stuart K. Roberts ◽  
Ricky Lim ◽  
Simone Strasser ◽  
Amanda Nicoll ◽  
Alessia Gazzola ◽  
...  

2003 ◽  
Vol 124 (4) ◽  
pp. A785 ◽  
Author(s):  
Sajid Jalil ◽  
Ahmet Gurakar ◽  
Harlan Wright ◽  
Ted Bader ◽  
Anthony Sebastian ◽  
...  

2017 ◽  
Vol 15 (12) ◽  
pp. 1950-1956.e1 ◽  
Author(s):  
Cumali Efe ◽  
Hannes Hagström ◽  
Henriette Ytting ◽  
Rahima A. Bhanji ◽  
Niklas F. Müller ◽  
...  

2019 ◽  
Vol 31 (7) ◽  
pp. 873-877 ◽  
Author(s):  
Zhen-Jun Yu ◽  
Lu-Lu Zhang ◽  
Ting-Ting Huang ◽  
Jian-Sheng Zhu ◽  
Ze-Bao He

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 490-490 ◽  
Author(s):  
A ADAMS ◽  
R GISH ◽  
E WAKIL ◽  
N BZOWEJ ◽  
E DOO ◽  
...  

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