scholarly journals Age-related metabolic changes limit efficacy of deoxynucleoside-based therapy in thymidine kinase 2-deficient mice

EBioMedicine ◽  
2019 ◽  
Vol 46 ◽  
pp. 342-355 ◽  
Author(s):  
Cora Blázquez-Bermejo ◽  
David Molina-Granada ◽  
Ferran Vila-Julià ◽  
Daniel Jiménez-Heis ◽  
Xiaoshan Zhou ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Metabolic Changes ◽  
Age Related ◽  
Deficient Mice ◽  
Thymidine Kinase 2

scholarly journals Long Term Expression ofDrosophila melanogasterNucleoside Kinase in Thymidine Kinase 2-deficient Mice with No Lethal Effects Caused by Nucleotide Pool Imbalances

2014 ◽  
Vol 289 (47) ◽  
pp. 32835-32844 ◽  
Author(s):  
Shuba Krishnan ◽  
João A. Paredes ◽  
Xiaoshan Zhou ◽  
Raoul V. Kuiper ◽  
Kjell Hultenby ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Lethal Effects ◽  
Deficient Mice ◽  
Thymidine Kinase 2

scholarly journals Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

2008 ◽  
Vol 17 (15) ◽  
pp. 2329-2335 ◽  
Author(s):  
X. Zhou ◽  
N. Solaroli ◽  
M. Bjerke ◽  
J. B. Stewart ◽  
B. Rozell ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Thymidine Kinase ◽  
Progressive Loss ◽  
Deficient Mice ◽  
Thymidine Kinase 2

Hematopoiesis in the thymidine kinase 2 deficient mouse model of mitochondrial DNA depletion syndrome

2010 ◽  
Vol 33 (3) ◽  
pp. 231-236 ◽  
Author(s):  
Xiaoshan Zhou ◽  
Magnus Johansson ◽  
Nicola Solaroli ◽  
Björn Rozell ◽  
Alf Grandien ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Mouse Model ◽  
Thymidine Kinase ◽  
Deficient Mouse ◽  
Mitochondrial Dna Depletion ◽  
Mitochondrial Dna Depletion Syndrome ◽  
Thymidine Kinase 2

scholarly journals Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): Present and future

2008 ◽  
Vol 28 (5) ◽  
pp. 797-820 ◽  
Author(s):  
María-Jesús Pérez-Pérez ◽  
Eva-María Priego ◽  
Ana-Isabel Hernández ◽  
Olga Familiar ◽  
María-José Camarasa ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Physiological Role ◽  
Thymidine Kinase 2 ◽  
Specific Inhibitors

scholarly journals A low glycemic diet protects disease-prone Nrf2-deficient mice against age-related macular degeneration

2020 ◽  
Vol 150 ◽  
pp. 75-86 ◽  
Author(s):  
Sheldon Rowan ◽  
Shuhong Jiang ◽  
Min-Lee Chang ◽  
Jonathan Volkin ◽  
Christa Cassalman ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Deficient Mice
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