scholarly journals Refining the Role of Left Atrial Strain in Heart Failure with Reduced Ejection Fraction

2021 ◽  
Author(s):  
Alessandro Malagoli ◽  
Luca Rossi ◽  
Alessia Zanni ◽  
Concetta Sticozzi ◽  
Massimo Francesco Piepoli ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Left Atrial Strain ◽  
Reduced Ejection Fraction ◽  
Atrial Strain

scholarly journals Impaired left atrial strain predicts abnormal exercise haemodynamics in heart failure with preserved ejection fraction

2019 ◽  
Vol 21 (4) ◽  
pp. 495-505 ◽  
Author(s):  
Fernando Telles ◽  
Shane Nanayakkara ◽  
Shona Evans ◽  
Hitesh C. Patel ◽  
Justin A. Mariani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

scholarly journals Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction

2019 ◽  
Vol 21 (7) ◽  
pp. 891-900 ◽  
Author(s):  
Yogesh N.V. Reddy ◽  
Masaru Obokata ◽  
Alexander Egbe ◽  
Jeong Hoon Yang ◽  
Sorin Pislaru ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Diagnostic Evaluation ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

Left atrial strain in heart failure with preserved ejection fraction

Herz ◽  
2016 ◽  
Vol 42 (2) ◽  
pp. 194-199 ◽  
Author(s):  
S. M. Aung ◽  
A. Güler ◽  
Y. Güler ◽  
A. Huraibat ◽  
C. Y. Karabay ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain

Simple and additive diagnostic modalities for the screening of heart failure with preserved ejection fraction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
B Illes ◽  
G Agoston ◽  
L Gargani ◽  
I Szabo ◽  
N Polestyuk-Nemeth ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Lung Ultrasound ◽  
High Morbidity ◽  
Pulmonary Congestion ◽  
Left Atrial Strain ◽  
Diagnostic Power ◽  
Atrial Strain ◽  
B Lines

Abstract Background Nearly half of all patients with heart failure (HF) symptoms have an EF that is preserved (HFpEF). The prevalence of HFpEF is rising, with high morbidity, mortality. The diagnosis of HFpEF is particularly challenging. Lung ultrasound (LUS) and left atrial strain are promising screening and diagnostic tools to assess pulmonary congestion and left atrial dysfunction in patients with suspected HFpEF. Aim To evaluate the relationship between patients symptoms, pro-BNP level with LUS and left atrial strain, as well to assess the diagnostic power of B-lines in HFpEF population. Methods 82 consecutive patients (57 women, mean age 70±6 years) with clinical signs of heart failure were prospectively enrolled. Exclusion criteria were: ejection fraction <55%, more than mild mitral and/or aortic valve disease, pulmonary disease, pulmonary arterial hypertension. Within one hour all patients underwent comprehensive echocardiographic evaluation including left atrial strain analysis (peak atrial longitudinal strain-LASr), lung ultrasound assessment of B-lines on the anterolateral and posterior chest wall, and NT-proBNP levels. Results In 45 patients (54%) a significant number of B-lines (≥15) were observed. We found a positive correlation between the number of B-lines and NT-proBNP levels (p<0.0001, r=0.67), left atrial volume (p<0.0001, r=0.45), and LASr (p<0.005, r=−0.4). We also found week correlation between the number of B-lines and E/e' ratio (p<0.003, r=0.3), and between E/e' ratio and NT-proBNP level (p<0.05, r=0.2). We also assessed the diagnostic ability of B-lines to predict markedly elevated pro-BNP level (≥125pg/ml), AUC was 0.85, with specificity of 64% and sensitivity of 85% (Figure 1). The number of B lines also correlated with the H2FPEF score (p<0.001, r=0.4). Conclusion LUS is a simple, feasible tool to detect pulmonary congestion in HFpEF and it has an adequate diagnostic power to predict elevated NTpro-BNP level. LASr is promising too, which better reflects pulmonary congestion and elevated NT-proBNP values than the conventional echocardiographic parameters. Figure 1. ROC curve Blines predict high NTproBNP Funding Acknowledgement Type of funding source: None

P1481B-lines and left atrial strain in outpatients with suspected heart failure with preserved ejection fraction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G Agoston ◽  
L Gargani ◽  
I Szabo ◽  
B Illes ◽  
A Varga
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Lung Ultrasound ◽  
Preserved Ejection Fraction ◽  
Pulmonary Congestion ◽  
Left Atrial Strain ◽  
Atrial Strain ◽  
Left Atrial Dysfunction ◽  
B Lines

Abstract Background Heart Failure with Preserved Ejection Fraction (HFpEF) is a growing healthcare burden and its prevalence is increasing. Diagnosing HFpEF is challenging. Lung ultrasound (LUS) and left atrial strain are promising tools to assess pulmonary congestion and left atrial dysfunction in outpatient settings in patients with suspected HFpEF. Aim To evaluate the correlation of LUS B-lines with left atrial strain in patients with HFpEF. Methods Thirty-six consecutive patients (24 women, mean age 70±6 years) with clinical signs of heart failure were prospectively enrolled. Exclusion criteria were: ejection fraction <55%, more than mild mitral and/or aortic valve disease, pulmonary disease, pulmonary arterial hypertension. Within one hour all patients underwent comprehensive echocardiographic evaluation including left atrial strain analysis (peak atrial longitudinal strain-PALS), lung ultrasound assessment of B-lines on the antero-lateral and posterior chest wall, and NT-proBNP levels. Results The mean ejection fraction was 65.5±8.6%. In 28 patients (85%) a significant number of B-lines (≥15) was observed. We found a positive correlation between the number of B-lines and NT-proBNP levels (p<0.0001, r: 0.76, Figure 1.), left atrial volume (p<0.05, r: 0.45), and PALS (p<0.05, r: −0.5, Figure 2.). We didn't found any correlation between the number of B-lines and E/e'ratio (p=0.1, r: 0.28), or between E/e' ratio and NT-proBNP level (p=0.2, r: 0.2). Conclusion LUS is a simple, feasible tool to detect pulmonary congestion in HFpEF and it seems to better characterize these patients. B-lines correlate well with NT-proBNP values and with parameters of left atrial dysfunction. PALS is a promising too which better reflects pulmonary congestion and elevated NT-proBNP values than the conventional echocardiographic parameter E/e'.

scholarly journals P5655Influence of left atrial strain and stiffness on haemodynamics in heart failure with preserved ejection fraction

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
F Telles ◽  
S Nanayakkara ◽  
S Evans ◽  
D Vizi ◽  
J William ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Left Atrial ◽  
Preserved Ejection Fraction ◽  
Left Atrial Strain ◽  
Atrial Strain
Sign in / Sign up

Export Citation Format

Share Document