Marked elevation of creatine phosphokinase alone caused by sintilimab - beware of hypothyroid myopathy

2020 ◽  
Vol 128 ◽  
pp. 57-59 ◽  
Author(s):  
Jun Ni ◽  
Li Zhang ◽  
Xiaotong Zhang
Keyword(s):  
Creatine Phosphokinase ◽  
Marked Elevation ◽  
Hypothyroid Myopathy

scholarly journals Neuroleptic Malignant Syndrome: A Case Aimed at Raising Clinical Awareness

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Jad Al Danaf ◽  
John Madara ◽  
Caitlin Dietsche
Keyword(s):  
Bipolar Disorder ◽  
Differential Diagnosis ◽  
Neuroleptic Malignant Syndrome ◽  
Creatine Phosphokinase ◽  
Supportive Therapy ◽  
Medication List ◽  
Marked Elevation ◽  
Serum Creatine Phosphokinase ◽  
History Of ◽  
Clinical Awareness

A 60-year-old man with a history of bipolar disorder on risperidone, bupropion, and escitalopram was admitted for community acquired streptococcal pneumonia. Four days later, he developed persistent hyperthermia, dysautonomia, rigidity, hyporeflexia, and marked elevation of serum creatine phosphokinase. He was diagnosed with neuroleptic malignant syndrome (NMS) and improved with dantrolene, bromocriptine, and supportive therapy. This case emphasizes the importance of considering a broad differential diagnosis for fever in the ICU, carefully reviewing the medication list for all patients, and considering NMS in patients with fever and rigidity.

Absence of myoglobinuria in acute psychotic patients with marked elevation in serum creatine phosphokinase level

2001 ◽  
Vol 11 (2) ◽  
pp. 111-115 ◽  
Author(s):  
Haggai Hermesh ◽  
Iris Manor ◽  
Roni Shiloh ◽  
Ronit Weizman ◽  
Hanan Munitz
Keyword(s):  
Creatine Phosphokinase ◽  
Marked Elevation ◽  
Serum Creatine Phosphokinase ◽  
Creatine Phosphokinase Level

scholarly journals Marked Elevation of the Creatine Phosphokinase Level in a Patient Receiving Tenofovir

2002 ◽  
Vol 35 (9) ◽  
pp. 1137-1137 ◽  
Author(s):  
K. D. Shere‐Wolfe ◽  
J. R. Verley
Keyword(s):  
Creatine Phosphokinase ◽  
Marked Elevation ◽  
Creatine Phosphokinase Level

Antibody to Hepatitis G Mrus after a Vapour-Heated Factor Vlll Goncentrate

1990 ◽  
Vol 64 (02) ◽  
pp. 232-234 ◽  
Author(s):  
P M Mannucci ◽  
A R Zanetti ◽  
M Colombo ◽  
A Chistolini ◽  
R De Biasi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Factor Viii ◽  
Alanine Aminotransferase ◽  
Household Contact ◽  
Clotting Factor ◽  
Double Infection ◽  
Marked Elevation ◽  
Clotting Factor Concentrates

SummaryTo evaluate whether or not clotting factor concentrates exposed to virucidal procedures transmitted hepatitis C, sera obtained in 1984–1986 from 27 previously untreated hemophiliacs infused with a vapour-heated factor VIII concentrate were tested retrospectively for the antibody to the hepatitis C virus (anti- HCV). A 2-year-old hemophiliac, negative for anti-HCV before administration of concentrate, seroconverted at week 12 and remained anti-HCV positive thereafter. Both his parents were anti-HCV negative and he had no other household contact. The patient had also become HBsAg positive at week 8 and had at the same time a marked elevation of alanine aminotransferase. His double infection with the hepatitis B and C viruses indicates that hot vapour was not completely effective in inactivating these viruses.

scholarly journals A case of stercoral colitis with marked elevation of serum carcinoembryonic antigen

2020 ◽  
Vol 8 (4) ◽  
pp. 734-738 ◽  
Author(s):  
Kiyoto Takehara ◽  
Yuko Takehara ◽  
Satoshi Ueyama ◽  
Tatsunori Kobayashi
Keyword(s):  
Carcinoembryonic Antigen ◽  
Marked Elevation ◽  
Serum Carcinoembryonic Antigen

Eignung der Kapillarmikroskopie zur Diagnostik und Differenzierung einer ILD

2021 ◽  
pp. 1-3
Author(s):  
Sabine Adler
Keyword(s):  
Computed Tomography ◽  
Creatine Phosphokinase ◽  
Correct Diagnosis ◽  
Diagnostic Assessment ◽  
Idiopathic Inflammatory Myopathies ◽  
Inflammatory Myopathies ◽  
Nailfold Videocapillaroscopy ◽  
High Resolution Computed Tomography ◽  
Diagnostic Role

Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud’s phenomenon (RP) as possibly associated with systemic sclerosis (SSc). Recent insights have also highlighted its role in the diagnostic assessment of idiopathic inflammatory myopathies (IIMs). The aim of this study is to describe the diagnostic role of NVC in a series of 361 consecutive patients with interstitial lung disease (ILD). All the patients were assessed by clinical pulmonary and rheumatic examinations, blood exams, high-resolution computed tomography and NVC. NVC was considered positive only in the presence of avascular areas or giant capillaries, but also, the presence of bushy capillaries (BCs) was recorded. NVC was positive in 17.7% of ILD patients and in 78.1% of ILD patients associated with a diagnosis of connective tissue disease (CTD). In 25% of SSc-ILD patients, NVC proved necessary for a correct diagnosis. The presence of BCs and/or NVC positivity in ILD patients with normal levels of creatine phosphokinase is associated with amyopathic IIM, regardless the presence of RP. In conclusion, NVC is useful for the diagnostic assessment of incomplete forms of CTD and in amyopathic IIMs. NVC should be considered in the diagnostic assessment of ILD patients regardless of the presence of RP.

An improved batchwise chromatographic procedure for creatine phosphokinase (CPK) isoenzyme separation

1977 ◽  
Vol 17 (2) ◽  
pp. 141-152 ◽  
Author(s):  
James T. Wu ◽  
Lily H. Wu ◽  
Fred A. Ziter
Keyword(s):  
Creatine Phosphokinase ◽  
Chromatographic Procedure

MB Isoenzyme of Creatine Phosphokinase

CHEST Journal ◽  
1979 ◽  
Vol 75 (1) ◽  
pp. 88-90 ◽  
Author(s):  
Alon Marmor ◽  
Shlomo Keidor ◽  
Ehud Grenadir ◽  
Aoraham Palant
Keyword(s):  
Creatine Phosphokinase
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