DNA binding and DNA cleavage studies of a water soluble cobalt(II) complex containing dinitrogen Schiff base ligand: The effect of metal on the mode of binding

2010 ◽  
Vol 45 (9) ◽  
pp. 4239-4245 ◽  
Author(s):  
Nahid Shahabadi ◽  
Soheila Kashanian ◽  
Farivash Darabi
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Schiff Base Ligand ◽  
Dna Cleavage ◽  
Water Soluble

Syntheses of Zn(II) and Cu(II) Schiff base complexes using N,O donor Schiff base ligand: Crystal structure, DNA binding, DNA cleavage, docking and DFT study

Polyhedron ◽  
2018 ◽  
Vol 141 ◽  
pp. 153-163 ◽  
Author(s):  
Pravat Ghorai ◽  
Rumpa Saha ◽  
Sutanwi Bhuiya ◽  
Suman Das ◽  
Paula Brandão ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Schiff Base ◽  
Dna Binding ◽  
Schiff Base Ligand ◽  
Dna Cleavage ◽  
Schiff Base Complexes ◽  
Dft Study

scholarly journals Investigation of Antimicrobial, Antioxidant, and DNA Binding Studies of Bioactive Cu(II), Zn(II), Co(II), and Ni(II) Complexes of Pyrimidine Derivative Schiff Base Ligand

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Shahul Hameed Sukkur Saleem ◽  
Murugesan Sankarganesh ◽  
Paul Raj Adwin Jose ◽  
Karunganathan Sakthikumar ◽  
Liviu Mitu ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Schiff Base Ligand ◽  
Dna Cleavage ◽  
Radical Scavenging ◽  
Antioxidant Property ◽  
Antimicrobial Activities ◽  
Pyrimidine Derivative ◽  
Planar Geometry ◽  
Binding Studies

A new pyrimidine based Schiff base ligand (HL) and its four complexes of type [MLOAc]·nH2O (Cu(II), 1; Zn(II), 2; Co(II), 3; and Ni(II), 4) have been synthesized and characterized by elemental analysis, MS, 1H-NMR, FT-IR, UV-visible, and ESR techniques. The electronic and ESR spectral data suggested that complexes 1–4 possess square planar geometry. Antimicrobial activities of HL and complexes 1–4 were tested against four bacteria (Staphylococcus aureus, Staphylococcus pneumonia, Salmonella enterica typhi, and Haemophilus influenzae) and two fungal strains (Aspergillus flavus and Aspergillus niger). These results show that complexes 1–4 have good antimicrobial activity compared to HL. The DNA cleavage activity of HL and complexes 1–4 was monitored by the agarose gel electrophoresis method. The antioxidant property of the prepared compounds was assessed by using 2,2′-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method. DNA binding properties of HL and complexes 1–4 have been investigated by electronic absorption technique and viscometric measurements.

DNA cleavage mechanism by metal complexes of Cu(II), Zn(II) and VO(IV) with a schiff-base ligand

Biochimie ◽  
2021 ◽  
Vol 186 ◽  
pp. 43-50
Author(s):  
María R. Rodríguez ◽  
Martín J. Lavecchia ◽  
Beatriz S. Parajón-Costa ◽  
Ana C. González-Baró ◽  
María R. González-Baró ◽  
...  
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Dna Cleavage

Facile template synthesis of water-soluble triazine-based Schiff base ligand bridged-coordination polymers of Co(ii), Ni(ii), and Cu(ii): structure, biomolecular interactions, and cytotoxic activity

2019 ◽  
Vol 43 (34) ◽  
pp. 13371-13380 ◽  
Author(s):  
Sheikdawood Parveen ◽  
Thathan Premkumar ◽  
Hung Huy Nguyen ◽  
Subbiah Govindarajan
Keyword(s):  
Schiff Base ◽  
Cytotoxic Activity ◽  
Coordination Polymers ◽  
Schiff Base Ligand ◽  
Template Synthesis ◽  
Water Soluble ◽  
Biomolecular Interactions ◽  
First Time ◽  
Ct Dna

For the first time, a new hydrazone Schiff base ligand and its Co(ii), Ni(ii), and Cu(ii) complexes were synthesised and characterised. Their antioxidant and binding activities towards CT-DNA and BSA were evaluated.

Syntheses, crystal structures, DNA binding, DNA cleavage and DFT study of Co(iii) complexes involving azo-appended Schiff base ligands

2018 ◽  
Vol 42 (20) ◽  
pp. 16571-16582 ◽  
Author(s):  
Saikat Banerjee ◽  
Roumi Patra ◽  
Pravat Ghorai ◽  
Paula Brandão ◽  
Sougata Ghosh Chowdhury ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Crystal Structures ◽  
Dna Cleavage ◽  
Dft Study ◽  
Schiff Base Ligands

Herein, we have reported three new Co(iii) complexes involving azo-appended Schiff base ligands.

scholarly journals Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications

Polyhedron ◽  
2020 ◽  
Vol 175 ◽  
pp. 114167
Author(s):  
Moumita Chakraborty ◽  
Satyajit Mondal ◽  
Christine Cardin ◽  
Arnold L. Rheingold ◽  
Chitrangada Das Mukhopadhyay ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Schiff Base Ligand ◽  
Binding Activity ◽  
Dna Binding Activity ◽  
Bio Imaging
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