Discovery and characterization of novel imidazopyridine derivative CHEQ-2 as a potent CDC25 inhibitor and promising anticancer drug candidate

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.05.063 ◽

2014 ◽

Vol 82 ◽

pp. 293-307 ◽

Author(s):

Yu'ning Song ◽

Xiaoqian Lin ◽

Dongwei Kang ◽

Xiao Li ◽

Peng Zhan ◽

...

Keyword(s):

Anticancer Drug ◽

Download Full-text

Establishment and characterization of cancer cell populations and clones resistant to the anticancer drug candidate M2

10.14711/thesis-991012752464303412 ◽

2019 ◽

Author(s):

Jun Young Cha

Keyword(s):

Cancer Cell ◽

Anticancer Drug ◽

Drug Candidate ◽

Cell Populations

Download Full-text

Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.8b00525 ◽

2018 ◽

Vol 15 (11) ◽

pp. 4898-4911 ◽

Author(s):

Lu-Ning Li ◽

Lei Wang ◽

Yan-Na Cheng ◽

Zhan-Qi Cao ◽

Xin-Ke Zhang ◽

...

Keyword(s):

Molecular Mechanism ◽

Anticancer Drug ◽

Download Full-text

Thin-layer chromatographic characterization of metabolites formed from an AMPA antagonist drug candidate

JPC - Journal of Planar Chromatography - Modern TLC ◽

10.1556/jpc.14.2001.4.8 ◽

2001 ◽

Vol 14 (4) ◽

pp. 266-271 ◽

Author(s):

Katalin Migléczi ◽

István Hazai ◽

Katalin Jemnitz ◽

Márta Pátfalusi

Keyword(s):

Drug Candidate ◽

Ampa Antagonist ◽

Chromatographic Characterization

Download Full-text

In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4

Letters in Drug Design & Discovery ◽

10.2174/1570180811666140529004102 ◽

2014 ◽

Vol 11 (7) ◽

pp. 825-832 ◽

Author(s):

Wolfgang Walther ◽

Iduna Fichtner ◽

Frauke Hackenberg ◽

Wojciech Streciwilk ◽

Matthias Tacke

Keyword(s):

Anticancer Drug ◽

Drug Candidate ◽

Download Full-text

Incipient citrus polymethoxylated flavone Tangeretin as anticancer drug candidate: Mechanistic insights, limitations and possible solutions

Advances in Cancer Biology - Metastasis ◽

10.1016/j.adcanc.2021.100010 ◽

2021 ◽

pp. 100010

Author(s):

Alex Boye ◽

Imad Ahmad ◽

Sajad Fakhri ◽

Yaseen Hussain ◽

Haroon Khan

Keyword(s):

Anticancer Drug ◽

Download Full-text

Preparation and characterization of nanocomposites based on different zeolite frameworks as carriers for anticancer drug: zeolite Y versus ZSM-5

Polymer Bulletin ◽

10.1007/s00289-018-2472-1 ◽

2018 ◽

Vol 76 (5) ◽

pp. 2233-2252 ◽

Author(s):

M. Karimi ◽

M. Habibizadeh ◽

K. Rostamizadeh ◽

M. Khatamian ◽

B. Divband

Keyword(s):

Anticancer Drug ◽

Download Full-text

Synthesis and characterization of a novel pH-controllable composite hydrogel for anticancer drug delivery

New Journal of Chemistry ◽

10.1039/c1nj20672a ◽

2011 ◽

Vol 35 (12) ◽

pp. 2869 ◽

Author(s):

T. S. Anirudhan ◽

S. Sandeep

Keyword(s):

Drug Delivery ◽

Anticancer Drug ◽

Composite Hydrogel ◽

Synthesis And Characterization ◽

Anticancer Drug Delivery

Download Full-text

Synthesis and characterization of porous CaCO3 microspheres templated by yeast cells and the application as pH value-sensitive anticancer drug carrier

Colloids and Surfaces B Biointerfaces ◽

10.1016/j.colsurfb.2020.111545 ◽

2021 ◽

Vol 199 ◽

pp. 111545

Author(s):

Yan Wei ◽

Ruize Sun ◽

Hui Su ◽

Hao Xu ◽

Lichuang Zhang ◽

...

Keyword(s):

Anticancer Drug ◽

Ph Value ◽

Drug Carrier ◽

Yeast Cells ◽

Synthesis And Characterization

Download Full-text

Discovery of Novel Plasmodium falciparum HDAC1 Inhibitors with Dual-Stage Antimalarial Potency and Improved Safety Based on the Clinical Anticancer Drug Candidate Quisinostat

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.0c02104 ◽

2021 ◽

Vol 64 (4) ◽

pp. 2254-2271

Author(s):

Ruoxi Li ◽

Dazheng Ling ◽

Tongke Tang ◽

Zhenghui Huang ◽

Manjiong Wang ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Anticancer Drug ◽

Drug Candidate ◽

Download Full-text

Late-Stage Sulfoximination: Improved Synthesis of the Anticancer Drug Candidate Atuveciclib

Synthesis ◽

10.1055/s-0037-1610316 ◽

2018 ◽

Vol 51 (04) ◽

pp. 971-975 ◽

Author(s):

Vincent Reboul ◽

Thomas Glachet ◽

Xavier Franck

Keyword(s):

Anticancer Drug ◽

Drug Candidate ◽

Efficient Synthesis ◽

Reaction Conditions

An efficient synthesis of racemic atuveciclib was accomplished in five steps with an excellent 51% overall yield, using cheap reagents and mild reaction conditions. The key sulfoximination reaction was realized during the last step of the synthesis from the corresponding sulfide.

Download Full-text