Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors

2016 ◽  
Vol 109 ◽  
pp. 173-186 ◽  
Author(s):  
Damien Bosc ◽  
Elisabeth Mouray ◽  
Sandrine Cojean ◽  
Caio Haddad Franco ◽  
Philippe M. Loiseau ◽  
...  
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Antiparasitic Activity ◽  
Protein Farnesyltransferase

Protein Farnesyltransferase Inhibitors

2004 ◽  
Vol 1 (1) ◽  
pp. 97-128
Author(s):  
Semiramis Ayral-Kaloustian ◽  
Edward J. Salaski
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth

1998 ◽  
Vol 94 (1) ◽  
pp. 87-97 ◽  
Author(s):  
Kohei Yokoyama ◽  
Patty Trobridge ◽  
Frederick S Buckner ◽  
Jeffrey Scholten ◽  
Kenneth D Stuart ◽  
...  
Keyword(s):  
Cell Growth ◽  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase

scholarly journals Second Generation Tetrahydroquinoline-Based Protein Farnesyltransferase Inhibitors as Antimalarials

2007 ◽  
Vol 50 (19) ◽  
pp. 4585-4605 ◽  
Author(s):  
Pravin Bendale ◽  
Srinivas Olepu ◽  
Praveen Kumar Suryadevara ◽  
Vivek Bulbule ◽  
Kasey Rivas ◽  
...  
Keyword(s):  
Second Generation ◽  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase

scholarly journals Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice.

1994 ◽  
Vol 91 (19) ◽  
pp. 9141-9145 ◽  
Author(s):  
N. E. Kohl ◽  
F. R. Wilson ◽  
S. D. Mosser ◽  
E. Giuliani ◽  
S. J. deSolms ◽  
...  
Keyword(s):  
Nude Mice ◽  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase

Protein farnesyltransferase inhibitors

2003 ◽  
Vol 8 (1) ◽  
pp. 163-178 ◽  
Author(s):  
Julia E Head ◽  
Stephen RD Johnston
Keyword(s):  
Farnesyltransferase Inhibitors ◽  
Protein Farnesyltransferase
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