Synthesis and biological evaluation of deferiprone-resveratrol hybrids as antioxidants, Aβ 1–42 aggregation inhibitors and metal-chelating agents for Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.12.045 ◽

2017 ◽

Vol 127 ◽

pp. 174-186 ◽

Author(s):

Ping Xu ◽

Minkui Zhang ◽

Rong Sheng ◽

Yongmin Ma

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Chelating Agents ◽

Biological Evaluation ◽

Metal Chelating ◽

Aggregation Inhibitors ◽

Synthesis And Biological Evaluation

Download Full-text

Phthalimide‐(N‐alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer’s disease: Design, synthesis and biological evaluation

Chemical Biology & Drug Design ◽

10.1111/cbdd.13905 ◽

2021 ◽

Author(s):

Heng Zhang ◽

Qing Song ◽

Guangjun Yu ◽

Zhongcheng Cao ◽

Xiaoming Qiang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of novel radioiodinated imidazopyridine derivatives for amyloid-β imaging in Alzheimer’s disease

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.05.043 ◽

2014 ◽

Vol 22 (15) ◽

pp. 4189-4197 ◽

Author(s):

Chun-Jen Chen ◽

Kazunori Bando ◽

Hiroki Ashino ◽

Kazumi Taguchi ◽

Hideaki Shiraishi ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Imidazopyridine Derivatives ◽

Synthesis And Biological Evaluation

Download Full-text

Design, synthesis, and biological evaluation of compounds with a new scaffold as anti-neuroinflammatory agents for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.02.063 ◽

2018 ◽

Vol 149 ◽

pp. 129-138 ◽

Author(s):

Yuying Fang ◽

Wenjuan Xia ◽

Bao Cheng ◽

Pei Hua ◽

Huihao Zhou ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

Download Full-text

Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.07.031 ◽

2019 ◽

Vol 180 ◽

pp. 367-382 ◽

Author(s):

Changjun Zhang ◽

Ke Yang ◽

Sihang Yu ◽

Jing Su ◽

Shengli Yuan ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Monoamine Oxidase ◽

Biological Evaluation ◽

Monoamine Oxidase B ◽

Iron Chelates ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of 3-arylbenzofuranone derivatives as potential anti-Alzheimer’s disease agents

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2020.1740694 ◽

2020 ◽

Vol 35 (1) ◽

pp. 805-814 ◽

Author(s):

Jie Yang ◽

Yinling Yun ◽

Yuhang Miao ◽

Jie Sun ◽

Xiaojing Wang

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of ranitidine analogs as multiple-target-directed cognitive enhancers for the treatment of Alzheimer’s disease

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2016.09.072 ◽

2016 ◽

Vol 26 (22) ◽

pp. 5573-5579 ◽

Author(s):

Jie Gao ◽

Narasimha Midde ◽

Jun Zhu ◽

Alvin V. Terry ◽

Campbell McInnes ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Multiple Target ◽

Cognitive Enhancers ◽

Synthesis And Biological Evaluation

Download Full-text

Design, Synthesis, and Biological Evaluation of Dual-Target Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 9A (PDE9A) for the Treatment of Alzheimer’s Disease

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.8b00376 ◽

2018 ◽

Vol 10 (1) ◽

pp. 537-551 ◽

Author(s):

Jinhui Hu ◽

Ya-Dan Huang ◽

Tingting Pan ◽

Tianhua Zhang ◽

Tao Su ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Download Full-text

Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer’s disease: Design, synthesis, and biological evaluation

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103721 ◽

2020 ◽

Vol 98 ◽

pp. 103721 ◽

Author(s):

Ana Xu ◽

Feng He ◽

Xiangna Zhang ◽

Xiaoyang Li ◽

Yingying Ran ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

Download Full-text

Semi-synthesis and biological evaluation of flavone hybrids as multifunctional agents for the potential treatment of Alzheimer's disease

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103917 ◽

2020 ◽

Vol 100 ◽

pp. 103917

Author(s):

Shaochun Shi ◽

Huibin Wang ◽

Jian Wang ◽

Yvxi Wang ◽

Xiaobian Xue ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Potential Treatment ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112193 ◽

2020 ◽

Vol 192 ◽

pp. 112193 ◽

Author(s):

Hui-Ju Tseng ◽

Mei-Hsiang Lin ◽

Young-Ji Shiao ◽

Ying-Chen Yang ◽

Jung-Chun Chu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Synthesis And Biological Evaluation

Download Full-text