scholarly journals Enzymatic and solid-phase synthesis of new donepezil-based L- and d -glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia

2017 ◽  
Vol 130 ◽  
pp. 60-72 ◽  
Author(s):  
Leticia Monjas ◽  
Mariana P. Arce ◽  
Rafael León ◽  
Javier Egea ◽  
Concepción Pérez ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebral Ischemia ◽  
Glutamic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Pharmacological Evaluation ◽  
Glutamic Acid Derivatives

Solid-phase synthesis of Nα-benzyl-Nα-cinnamyl lysine and glutamic acid derivatives

2000 ◽  
Vol 41 (27) ◽  
pp. 5187-5191 ◽  
Author(s):  
Peter J Connolly ◽  
Kimberly N Beers ◽  
Steven K Wetter ◽  
William V Murray
Keyword(s):  
Glutamic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Glutamic Acid Derivatives

Enantioselective solution- and solid-phase synthesis of glutamic acid derivatives via Michael addition reactions

2001 ◽  
Vol 12 (6) ◽  
pp. 821-828 ◽  
Author(s):  
Martin J. O'Donnell ◽  
Francisca Delgado ◽  
Esteban Domı́nguez ◽  
Jesús de Blas ◽  
William L. Scott
Keyword(s):  
Glutamic Acid ◽  
Michael Addition ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Addition Reactions ◽  
Phase Synthesis ◽  
Glutamic Acid Derivatives

High-yield solid-phase synthesis of humanin, an Alzheimer’s disease associated 24-mer peptide, and humanin analogues

2005 ◽  
Author(s):  
Christos Zikos ◽  
Alexandra Evangelou ◽  
Dimitra Benaki ◽  
Emmanuel Mikros ◽  
Maria Pelecanou ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
High Yield ◽  
Phase Synthesis

An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid

Synlett ◽  
2014 ◽  
Vol 25 (15) ◽  
pp. 2221-2224 ◽  
Author(s):  
Paul Harris ◽  
Margaret Brimble ◽  
Ger Molenaar ◽  
Zaid Amso ◽  
G. Savage
Keyword(s):  
Glutamic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Neuroprotective Agent ◽  
Fmoc Solid Phase Synthesis

Solid-phase synthesis and pharmacological evaluation of novel nucleoside-tethered dinuclear platinum(II) complexes

2011 ◽  
Vol 21 (19) ◽  
pp. 5835-5838 ◽  
Author(s):  
Stefano D’Errico ◽  
Giorgia Oliviero ◽  
Vincenzo Piccialli ◽  
Jussara Amato ◽  
Nicola Borbone ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
Pharmacological Evaluation ◽  
Dinuclear Platinum
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