A comparison of two biorelevant in vitro drug release methods for nanotherapeutics based on advanced physiologically-based pharmacokinetic modelling

European Journal of Pharmaceutics and Biopharmaceutics ◽

10.1016/j.ejpb.2018.03.010 ◽

2018 ◽

Vol 127 ◽

pp. 462-470 ◽

Author(s):

Fabian Jung ◽

Lisa Nothnagel ◽

Fiona Gao ◽

Manuela Thurn ◽

Vitali Vogel ◽

...

Keyword(s):

Drug Release ◽

Pharmacokinetic Modelling ◽

In Vitro Drug Release ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data

European Journal of Clinical Pharmacology ◽

10.1007/s00228-013-1603-8 ◽

2013 ◽

Vol 70 (2) ◽

pp. 167-178 ◽

Author(s):

Anna Nordmark ◽

Anita Andersson ◽

Pawel Baranczewski ◽

Ewa Wanag ◽

Lars Ståhle

Keyword(s):

Interaction Potential ◽

In Vitro Metabolism ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling

Chemico-Biological Interactions ◽

10.1016/s0009-2797(01)00276-9 ◽

2001 ◽

Vol 138 (3) ◽

pp. 247-265 ◽

Author(s):

Jan J.P Bogaards ◽

Andreas P Freidig ◽

Peter J van Bladeren

Keyword(s):

Kinetic Data ◽

Enzyme Kinetic ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Prediction of Ketoconazole absorption using an updated in vitro transfer model coupled to physiologically based pharmacokinetic modelling

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2016.12.017 ◽

2017 ◽

Vol 100 ◽

pp. 42-55 ◽

Author(s):

Aaron Ruff ◽

Tom Fiolka ◽

Edmund S. Kostewicz

Keyword(s):

Transfer Model ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Potential for pharmacokinetic interactions between Schisandra sphenanthera and bosutinib, but not imatinib: in vitro metabolism study combined with a physiologically‐based pharmacokinetic modelling approach

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14303 ◽

2020 ◽

Vol 86 (10) ◽

pp. 2080-2094

Author(s):

Jeffry Adiwidjaja ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

In Vitro Metabolism ◽

Pharmacokinetic Modelling ◽

Schisandra Sphenanthera ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Pharmacokinetic Interactions ◽

Physiologically Based ◽

Metabolism Study ◽

Modelling Approach

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Using physiologically based pharmacokinetic modelling for in silico–in vitro–in vivo extrapolation to predict chemical exposure

Toxicology Letters ◽

10.1016/j.toxlet.2016.06.1484 ◽

2016 ◽

Vol 258 ◽

pp. S119-S120

Author(s):

M. Lawless ◽

H. Zhou ◽

G. Fraczkiewicz

Keyword(s):

In Silico ◽

Chemical Exposure ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based ◽

In Vivo Extrapolation

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Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2221 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Catia Marzolini

Keyword(s):

Drug Interactions ◽

Clinical Management ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation

British Journal of Clinical Pharmacology ◽

10.1111/bcp.13480 ◽

2018 ◽

Vol 84 (3) ◽

pp. 462-476 ◽

Author(s):

Thomas M. Polasek ◽

Geoffrey T. Tucker ◽

Michael J. Sorich ◽

Michael D. Wiese ◽

Titus Mohan ◽

...

Keyword(s):

Modelling And Simulation ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Physiologically based pharmacokinetic modelling: a sub-compartmentalized model of tissue distribution

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-007-9071-3 ◽

2007 ◽

Vol 34 (6) ◽

pp. 789-806 ◽

Author(s):

Max von Kleist ◽

Wilhelm Huisinga

Keyword(s):

Tissue Distribution ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Physiologically Based

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Physiologically‐based pharmacokinetic modelling to predict oprozomib CYP3A drug–drug interaction potential in patients with advanced malignancies

British Journal of Clinical Pharmacology ◽

10.1111/bcp.13817 ◽

2018 ◽

Vol 85 (3) ◽

pp. 530-539 ◽

Author(s):

Ying Ou ◽

Yang Xu ◽

Lia Gore ◽

R. Donald Harvey ◽

Alain Mita ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Advanced Malignancies ◽

Physiologically Based ◽

Drug Drug Interaction

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Development of a Korean‐specific virtual population for physiologically based pharmacokinetic modelling and simulation

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2178 ◽

2019 ◽

Vol 40 (3-4) ◽

pp. 135-150 ◽

Author(s):

Yun Kim ◽

Oliver Hatley ◽

Su‐jin Rhee ◽

Sojeong Yi ◽

Hyun A. Lee ◽

...

Keyword(s):

Modelling And Simulation ◽

Pharmacokinetic Modelling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based Pharmacokinetic Modelling ◽

Virtual Population ◽

Physiologically Based

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