scholarly journals A comparison of the effects of the dopamine partial agonists aripiprazole and (−)-3-PPP with quinpirole on stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry in vitro

2012 ◽  
Vol 686 (1-3) ◽  
pp. 60-65 ◽  
Author(s):  
John J. O'Connor ◽  
John P. Lowry
1990 ◽  
Vol 509 (1) ◽  
pp. 172-174 ◽  
Author(s):  
P. Palij ◽  
D.R. Bull ◽  
M.J. Sheehan ◽  
J. Millar ◽  
J. Stamford ◽  
...  

Neuroscience ◽  
1999 ◽  
Vol 95 (4) ◽  
pp. 1061-1070 ◽  
Author(s):  
Q.D. Walker ◽  
M.B. Rooney ◽  
R.M. Wightman ◽  
C.M. Kuhn

2009 ◽  
Vol 108 (3) ◽  
pp. 545-551 ◽  
Author(s):  
Carmel O’Neill ◽  
Alex Evers-Donnelly ◽  
David Nicholson ◽  
Kathy M. O’Boyle ◽  
John J. O’Connor

2020 ◽  
Author(s):  
Elizabeth N. Holly ◽  
M. Felicia Davatolhagh ◽  
Rodrigo A. España ◽  
Marc V. Fuccillo

Low-threshold spiking interneurons (LTSIs) in the dorsomedial striatum are potent modulators of goal-directed learning. Here, we uncover a novel function for LTSIs in locally and directly gating striatal dopamine, using in vitro fast scan cyclic voltammetry as well as in vivo GRAB-DA sensor imaging and pharmacology during operant learning. We demonstrate that LTSIs, acting via GABAB signaling, attenuate dopamine release, thereby serving as local coordinators of striatal plasticity.


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