Development of a population pharmacokinetic model to predict brain distribution and dopamine D2 receptor occupancy of raclopride in non-anesthetized rat

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2017.10.031 ◽

2018 ◽

Vol 111 ◽

pp. 514-525 ◽

Cited By ~ 4

Author(s):

Yin Cheong Wong ◽

Trayana Ilkova ◽

Rob C. van Wijk ◽

Robin Hartman ◽

Elizabeth C.M. de Lange

Keyword(s):

Population Pharmacokinetic Model ◽

Pharmacokinetic Model ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Population Pharmacokinetic ◽

Brain Distribution ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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P.3.05 In vivo123Iodobenzamide SPECT quantification of striatal dopamine D2 receptor occupancy of risperidone depot in patients with psychosis

European Neuropsychopharmacology ◽

10.1016/s0924-977x(04)90060-0 ◽

2004 ◽

Vol 14 ◽

pp. S49-S50

Author(s):

G. Wiesegger ◽

N. Klein ◽

T. Attarbaschi ◽

S. Asenbaum ◽

D. Winkler ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Striatal Dopamine ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Dopamine D2 Receptor Occupancy as a Predictor of Catalepsy in Rats: A Pharmacokinetic-Pharmacodynamic Modeling Approach

Pharmaceutical Research ◽

10.1007/s11095-014-1358-7 ◽

2014 ◽

Vol 31 (10) ◽

pp. 2605-2617 ◽

Cited By ~ 8

Author(s):

Martin Johnson ◽

Magdalena Kozielska ◽

Venkatesh Pilla Reddy ◽

An Vermeulen ◽

Hugh A. Barton ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Pharmacodynamic Modeling ◽

Modeling Approach ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Poster #217 PREDICTING DOPAMINE D2 RECEPTOR OCCUPANCY FOLLOWING ANTIPSYCHOTIC DOSE REDUCTION: A PILOTPETSTUDY

Schizophrenia Research ◽

10.1016/s0920-9964(12)71049-6 ◽

2012 ◽

Vol 136 ◽

pp. S359

Author(s):

Hiroyuki Uchida ◽

Robert R. Bies ◽

Takefumi Suzuki ◽

Ariel Graff-Guerrero ◽

Bruce G. Pollock ◽

...

Keyword(s):

Dose Reduction ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Relationships between dopamine-D2 receptor occupancy and dopa decarboxylase activity. A pet-study in neuroleptic treated patients with patient with schizophrenia

Schizophrenia Research ◽

10.1016/s0920-9964(97)88733-6 ◽

1998 ◽

Vol 29 (1-2) ◽

pp. 167

Author(s):

F.-A. Wiesel ◽

M. Bela ◽

O.E. Gefvert ◽

G. Hagberg ◽

B. Långström ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Dopa Decarboxylase ◽

Decarboxylase Activity ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Poster #218 DOPAMINE D2 RECEPTOR OCCUPANCY AND COGNITION IN SCHIZOPHRENIA: ANALYSIS OF THE CATIE DATA

Schizophrenia Research ◽

10.1016/s0920-9964(12)71050-2 ◽

2012 ◽

Vol 136 ◽

pp. S359

Author(s):

Hiroyuki Uchida ◽

Hitoshi Sakurai ◽

Robert R. Bies ◽

Scott Stroup ◽

Richard S.E. Keefe ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Physiologically Based Modeling Approach to Predict Dopamine D2 Receptor Occupancy of Antipsychotics in Brain: Translation From Rat to Human

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1365 ◽

2019 ◽

Vol 59 (5) ◽

pp. 731-747 ◽

Cited By ~ 2

Author(s):

Yin Cheong Wong ◽

Maddalena Centanni ◽

Elizabeth C. M. Lange

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Modeling Approach ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy ◽

Physiologically Based

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Subjective Experience and Striatal Dopamine D2 Receptor Occupancy in Patients With Schizophrenia Stabilized by Olanzapine or Risperidone

American Journal of Psychiatry ◽

10.1176/appi.ajp.157.6.1019 ◽

2000 ◽

Vol 157 (6) ◽

pp. 1019-1020 ◽

Cited By ~ 86

Author(s):

L. de Haan

Keyword(s):

Subjective Experience ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Striatal Dopamine ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Dopamine D2 receptor occupancy by olanzapine or risperidone in young patients with schizophrenia

Psychiatry Research Neuroimaging ◽

10.1016/s0925-4927(99)00032-3 ◽

1999 ◽

Vol 92 (1) ◽

pp. 33-44 ◽

Cited By ~ 30

Author(s):

Jules Lavalaye ◽

Donald H. Linszen ◽

Jan Booij ◽

Liesbeth Reneman ◽

Berthold P.R. Gersons ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Young Patients ◽

Receptor Occupancy ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Hyperprolactinemia and estimated dopamine D2 receptor occupancy in patients with schizophrenia: Analysis of the CATIE data

Progress in Neuro-Psychopharmacology and Biological Psychiatry ◽

10.1016/j.pnpbp.2013.05.010 ◽

2013 ◽

Vol 45 ◽

pp. 178-182 ◽

Cited By ~ 15

Author(s):

Takashi Tsuboi ◽

Robert R. Bies ◽

Takefumi Suzuki ◽

David C. Mamo ◽

Bruce G. Pollock ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy

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Estimation of the time-course of dopamine D2 receptor occupancy in living human brain from plasma pharmacokinetics of antipsychotics

The International Journal of Neuropsychopharmacology ◽

10.1017/s1461145703003912 ◽

2004 ◽

Vol 7 (1) ◽

pp. 19-26 ◽

Cited By ~ 36

Author(s):

Akihiro Takano ◽

Tetsuya Suhara ◽

Yoko Ikoma ◽

Fumihiko Yasuno ◽

Jun Maeda ◽

...

Keyword(s):

Human Brain ◽

Time Course ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Occupancy ◽

Dopamine D2 ◽

Dopamine D2 Receptor Occupancy ◽

Plasma Pharmacokinetics

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