Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2017.11.011 ◽

2018 ◽

Vol 112 ◽

pp. 168-179 ◽

Author(s):

Yumi Yamamoto ◽

Pyry A. Välitalo ◽

Yin Cheong Wong ◽

Dymphy R. Huntjens ◽

Johannes H. Proost ◽

...

Keyword(s):

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01672 ◽

2020 ◽

Vol 10 ◽

Author(s):

Jeffry Adiwidjaja ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Optimal Dosing ◽

Physiologically Based ◽

Dosing Regimens

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A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1992 ◽

2016 ◽

Vol 37 (1) ◽

pp. 15-27 ◽

Author(s):

Ian Templeton ◽

Paulien Ravenstijn ◽

Carlo Sensenhauser ◽

Jan Snoeys

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically-Based Pharmacokinetic Modeling Approach Using Biomonitoring Data in Order to Assess the Contribution of Drinking Water for the Achievement of an Optimal Fluoride Dose for Dental Health in Children

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph15071358 ◽

2018 ◽

Vol 15 (7) ◽

pp. 1358 ◽

Author(s):

Keven Jean ◽

Nancy Wassef ◽

Fabien Gagnon ◽

Mathieu Valcke

Keyword(s):

Drinking Water ◽

Dental Health ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug–Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients

Drug Metabolism and Disposition ◽

10.1124/dmd.116.073585 ◽

2017 ◽

Vol 45 (4) ◽

pp. 361-374 ◽

Author(s):

Heidi J. Einolf ◽

Jocelyn Zhou ◽

Christina Won ◽

Lai Wang ◽

Sam Rebello

Keyword(s):

Drug Interactions ◽

Cancer Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Evaluation of the Drug–Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP ‐5862, Using a Physiologically‐Based Pharmacokinetic Modeling Approach

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12408 ◽

2019 ◽

Vol 8 (7) ◽

pp. 489-499 ◽

Author(s):

Diansong Zhou ◽

Terry Podoll ◽

Yan Xu ◽

Ganesh Moorthy ◽

Karthick Vishwanathan ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Active Metabolite ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Journal of Pharmaceutical Sciences ◽

10.1002/jps.22550 ◽

2011 ◽

Vol 100 (10) ◽

pp. 4127-4157 ◽

Author(s):

Patrick Poulin ◽

Rhys D.O. Jones ◽

Hannah M. Jones ◽

Christopher R. Gibson ◽

Malcolm Rowland ◽

...

Keyword(s):

Plasma Concentration ◽

Predictive Models ◽

Pharmacokinetic Modeling ◽

Human Pharmacokinetics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Time Profiles ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Concentration Time ◽

Physiologically Based

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A Physiologically Based Pharmacokinetic Modeling Approach to Predict Disease–Drug Interactions: Suppression of CYP3A by IL-6

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2013.79 ◽

2013 ◽

Vol 94 (2) ◽

pp. 260-268 ◽

Author(s):

K K Machavaram ◽

L M Almond ◽

A Rostami-Hodjegan ◽

I Gardner ◽

M Jamei ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug-Drug Interactions of Buprenorphine After Subcutaneous Administration of CAM2038 With Perpetrators of CYP3A4

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.10.035 ◽

2018 ◽

Vol 107 (3) ◽

pp. 942-948

Author(s):

Tao Liu ◽

Jogarao V.S. Gobburu

Keyword(s):

Drug Interactions ◽

Subcutaneous Administration ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Evaluation of the Impacts of Formulation Parameters on the Pharmacokinetics and Bioequivalence of Risperidone Orodispersible Film: a Physiologically Based Pharmacokinetic Modeling Approach

AAPS PharmSciTech ◽

10.1208/s12249-020-01728-7 ◽

2020 ◽

Vol 21 (7) ◽

Author(s):

Fang Chen ◽

Hongrui Liu ◽

Bing Wang ◽

Zhou Yang ◽

Yusheng Chen ◽

...

Keyword(s):

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Formulation Parameters

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