scholarly journals Outcome of total hip arthroplasty for avascular necrosis of femoral head in systemic lupus erythematosus patients: A comparative study

2022 ◽  
Vol 44 (3) ◽  
pp. 181-184
Author(s):  
Nora Y. Elsaid ◽  
Tarek A. Saad
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Femoral Head ◽  
Total Hip Arthroplasty ◽  
Comparative Study ◽  
Avascular Necrosis ◽  
Hip Arthroplasty ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Total Hip ◽  
Necrosis Of Femoral Head

Outcomes of Primary Total Hip Arthroplasty in Systemic Lupus Erythematosus With a Proximally-Coated Cementless Stem

2013 ◽  
Vol 28 (9) ◽  
pp. 1663-1666 ◽  
Author(s):  
Kimona Issa ◽  
Qais Naziri ◽  
Vijay J. Rasquinha ◽  
Tiffany Tatevossian ◽  
Bhaveen H. Kapadia ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Lupus Erythematosus ◽  
Cementless Stem ◽  
Systemic Lupus ◽  
Total Hip ◽  
Primary Total Hip Arthroplasty

scholarly journals Long-term results of hip arthroplasty and determination of unfavorable risk factors for early development of osteonecrosis in patients with systemic lupus erythematosus

2021 ◽  
Vol 59 (3) ◽  
pp. 351-356
Author(s):  
V. V. Mukhanov ◽  
S. A. Makarov ◽  
M. A. Makarov ◽  
T. V. Popkova
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Total Hip Arthroplasty ◽  
Early Development ◽  
Hip Arthroplasty ◽  
Lupus Erythematosus ◽  
Underlying Disease ◽  
Long Term Results ◽  
Systemic Lupus ◽  
Total Hip

Aim of the study – to determine the risk factors for the early development of osteonecrosis and to analyze the results of surgical treatment of patients with systemic lupus erythematosus in the long term after total hip arthroplasty.Materials and methods. The study group included 42 patients with systemic lupus erythematosus (SLE) complicated by osteonecrosis (ON) of the femoral head, who underwent 59 total hip arthroplasty (THA) operations. Before surgery and 6–21 years after THA, in order to assess the long-term results of surgical treatment of patients, the following was assessed: activity of the underlying disease – according to the SLEDAI-2K (Systemic Lupus Erythematosus Disease Activity Index 2000); the severity of irreversible changes in internal organs – according to the SLICC/ACR index of damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology); the clinical and functional state of the hip joint – according to the HHS (Harris Hip Score); the intensity of pain syndrome – according to the visual analogue scale (VAS); quality of life (QOL) – using the SF-36 questionnaire. The concentration of antibodies to cardiolipin (aCL) of IgM and IgG isotypes was determined by enzyme-linked immunosorbent assay (normal range – 0.0–10.0 GPL for IgM, 0–7 MPL for IgG).Results. After 6–21 years of follow-up after THA, there was a statistically significant decrease in pain intensity according to VAS, improvement according to the HHS from 40.0±14.9 to 83.3±17.4 points, SLE activity according to the SLEDAI-2K from 0 to 20 points (median – 4 [4; 8] points) before surgery and from 0 to 41 points (median – 0 [0; 4] points) after a long period of observation. There was a pronounced statistically significant positive dynamics for all QOL indicators studied (p≤0.005 in all cases). The most significant changes were found on the scales RE (Role-Emotional), RP (Role-Physical Functioning) and BP (Bodily Pain). The early development of ON was associated with the degree of activity of the underlying disease, the cumulative dose of glucocorticoids, kidney damage and arthritis in the first year from the onset of SLE, as well as hematological disorders and the presence of aCL in the blood serum 3 years before the onset of ON. The total number of complications was 10.2%.Conclusion. Total hip arthroplasty in patients with systemic lupus erythematosus can achieve a statistically significant reduction in pain intensity, increase functional activity and improve their quality of life.

scholarly journals Total Hip Arthroplasty in Systemic Lupus Erythematosus: A Systematic Review

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
John W. Kennedy ◽  
Wasim Khan
Keyword(s):  
Systematic Review ◽  
Systemic Lupus Erythematosus ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Lupus Erythematosus ◽  
Postoperative Outcomes ◽  
Harris Hip Score ◽  
Systemic Lupus ◽  
Total Hip

The prognosis of systemic lupus erythematosus (SLE) has greatly improved in recent years, resulting in an increased number of patients reporting musculoskeletal complications such as osteonecrosis of the femoral head. Total hip arthroplasty (THA) can be utilised to alleviate the pain associated with this; however postoperative outcomes in patients with SLE are uncertain. A systematic review of the literature was conducted to identify articles presenting results of THA in SLE, and nine suitable papers were found. All papers were level IV evidence. Pooling the results, a total of 162 patients underwent 214 total hip arthroplasties. Mean follow-up was 72.5 months. The mean Harris Hip Score improved from 45.5 preoperatively to 88.6 and last follow-up. Seventeen percent of patients experienced at least one complication. Superficial wound infection occurred in 3.3%. Revision was required in 2.8% of cases. The mortality rate was 18.5% however no deaths were attributable to undergoing THA. Given the paucity of data present in the literature, more studies are required to adequately assess the postoperative outcomes of THA in patients with SLE, particularly complication rates.

Patients with Systemic Lupus Erythematosus Have Increased Risk of Short-term Adverse Events after Total Hip Arthroplasty

2016 ◽  
Vol 43 (8) ◽  
pp. 1498-1502 ◽  
Author(s):  
Jordan E. Roberts ◽  
Lisa A. Mandl ◽  
Edwin P. Su ◽  
David J. Mayman ◽  
Mark P. Figgie ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Total Hip Arthroplasty ◽  
Adverse Events ◽  
Renal Disease ◽  
Hip Arthroplasty ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Total Hip ◽  
Increased Risk ◽  
Comorbidity Scores

Objective.Total hip arthroplasty (THA) is performed more frequently in patients with systemic lupus erythematosus (SLE) than in the general population. However, whether patients with SLE have higher complication rates than patients with osteoarthritis (OA) is unknown. This study compares adverse events (AE) in SLE with OA controls.Methods.Patients in our institution’s registry were eligible. SLE was identified by the International Classification of Diseases, 9th ed code. AE were identified by chart review and questionnaire. Patients with SLE were matched with OA controls. Multivariate regression was performed to identify independent predictors of AE.Results.Fifty-eight patients with SLE THA were matched with 116 OA controls. Of the patients with SLE, 47.4% had Charlson-Deyo comorbidity scores (excluding SLE) > 1 versus 13.1% of OA (p < 0.0001). Length of stay was longer for SLE (6.0 days vs 4.7 days, p = 0.0008). Patients with SLE had more falls (10.3% vs 1.7%, p = 0.017), deep vein thrombosis (5.2% vs 0%, p = 0.036), acute renal disease (8.6% vs 0%, p = 0.004), wound infections (6.9% vs 0.9%, p = 0.043), and revision surgeries (5.2% vs 0%, p = 0.036). In a logistic regression controlling for comorbidities, SLE had an increased risk of AE (OR 3.77, 95% CI 1.74–8.16). Comorbidity scores were not significantly associated with AE. Among those with SLE, there were no significant differences in AE in those taking corticosteroids.Conclusion.SLE is an independent risk factor for AE after THA. Patients with SLE had higher rates of falls, acute renal disease, infections, and revision surgeries than matched OA controls. Further research is needed to understand the causes of increased AE in patients with SLE.

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