Diffusion-weighted imaging for the follow-up of patients after matrix-associated autologous chondrocyte transplantation

2010 ◽  
Vol 73 (3) ◽  
pp. 622-628 ◽  
Author(s):  
Klaus M. Friedrich ◽  
Tallal C. Mamisch ◽  
Christina Plank ◽  
Georg Langs ◽  
Stefan Marlovits ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Autologous Chondrocyte Transplantation ◽  
Chondrocyte Transplantation ◽  
Diffusion Weighted ◽  
Autologous Chondrocyte

Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)—5-year follow-up

The Knee ◽  
2006 ◽  
Vol 13 (3) ◽  
pp. 194-202 ◽  
Author(s):  
Peter Behrens ◽  
Thomas Bitter ◽  
Bodo Kurz ◽  
Martin Russlies
Keyword(s):  
Autologous Chondrocyte Transplantation ◽  
Chondrocyte Transplantation ◽  
Autologous Chondrocyte

scholarly journals Mosaicplasty versus Matrix-Assisted Autologous Chondrocyte Transplantation for Knee Cartilage Defects: A Long-Term Clinical and Imaging Evaluation

2020 ◽  
Vol 10 (13) ◽  
pp. 4615
Author(s):  
Stefano Zaffagnini ◽  
Angelo Boffa ◽  
Luca Andriolo ◽  
Davide Reale ◽  
Maurizio Busacca ◽  
...  
Keyword(s):  
Activity Level ◽  
Autologous Chondrocyte Transplantation ◽  
Cartilage Defects ◽  
Chondrocyte Transplantation ◽  
Knee Cartilage ◽  
Cartilage Lesions ◽  
Long Term Follow Up ◽  
Autologous Chondrocyte

Different surgical procedures have been proposed over the past few years to treat cartilage lesions. The aim of this study was to compare mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) at long-term follow-up. Forty-three patients were included: 20 mosaicplasty and 23 MACT. Patients were evaluated before and 12 years after surgery with the International Knee Documentation Committee (IKDC) subjective and objective scores for symptoms and function, and with the Tegner score for activity level. Magnetic Resonance Imaging (MRI) was used to evaluate repair tissue with the MOCART 2.0 score. Mosaicplasty and MACT showed good clinical and MRI results (IKDC subjective score 75.3 ± 21.8 and 81.8 ± 13.0, both p < 0.0005). Mosaicplasty presented a 10% reoperation rate and a 25% overall failure rate, while no failures were documented in MACT (p = 0.016). While size did not influence the results in the MACT group, mosaicplasty presented lower IKDC objective and Tegner scores in lesions bigger than 2 cm2 (p = 0.031 and p = 0.014, respectively). Mosaicplasty and MACT presented both satisfactory clinical and MRI results at long-term follow-up. However, for larger lesions, MACT presented better subjective and objective outcomes, as well as less failures, which should be considered when choosing the most suitable treatment for patients affected by knee cartilage lesions.

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