Evaluating the effectiveness of prophylactic central neck dissection with total thyroidectomy for cN0 papillary thyroid carcinoma: An updated meta-analysis

2017 ◽  
Vol 43 (11) ◽  
pp. 1989-2000 ◽  
Author(s):  
Wan-jun Zhao ◽  
Han Luo ◽  
Yi-mei Zhou ◽  
Wen-yu Dai ◽  
Jing-qiang Zhu
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Total Thyroidectomy ◽  
Neck Dissection ◽  
Meta Analysis ◽  
Central Neck Dissection ◽  
Central Neck ◽  
Papillary Thyroid ◽  
Prophylactic Central Neck Dissection

scholarly journals The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Doh Young Lee ◽  
Kyoung Ho Oh ◽  
Jae-Gu Cho ◽  
Soon-Young Kwon ◽  
Jeong-Soo Woo ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Total Thyroidectomy ◽  
Neck Dissection ◽  
Disease Recurrence ◽  
Central Neck Dissection ◽  
Complication Rates ◽  
Central Neck ◽  
Papillary Thyroid ◽  
Prophylactic Central Neck Dissection

Objectives. This study evaluated the benefits of performing prophylactic central neck dissection (CND) with total thyroidectomy (TT) in management of papillary thyroid carcinoma (PTC) patients who were clinically node-negative at presentation.Methods.A total of 257 patients with stage T1 or T2 PTC and without preoperative evidence of lymph node involvement (N0) were enrolled in this prospective study. The patients were randomly assigned to two groups: (1) a total thyroidectomy (TT) group (n=104) or (2) a TT plus CND group (n=153). The two groups were compared for their perioperative data, complication rates, disease recurrence rates, and clinical outcomes.Results. The two groups of patients were similar in age, sex ratio, follow-up duration, and tumor size (P=0.227, 0.359, 0.214, and 0.878, resp.). The two groups showed similar rates of disease recurrence (3.9% in the TT group versus 3.3% in the TT plus CND group); however, complications occurred more frequently in the TT plus CND group; especially transient hypocalcemia (P=0.043).Conclusions.Patients treated with TT plus CND had a higher rate of complications with similar recurrence rate. We believe that CND may not be routinely recommended when treating patients with PTC.

scholarly journals The Effect of Prophylactic Central Neck Dissection During Hemithyroidectomy on Locoregional Recurrence in Patients With Papillary Thyroid Carcinoma: A Meta-Analysis

2020 ◽  
Vol 13 (2) ◽  
pp. 194-202 ◽  
Author(s):  
Soon-Hyun Ahn ◽  
Won Sik Kim
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Neck Dissection ◽  
Locoregional Recurrence ◽  
Meta Analysis ◽  
Central Compartment ◽  
Central Neck Dissection ◽  
Central Neck ◽  
Papillary Thyroid ◽  
Prophylactic Central Neck Dissection

Objectives. Hemithyroidectomy is commonly performed in patients with low- to intermediate-risk papillary thyroid carcinoma. The purpose of this meta-analysis was to evaluate the effect of prophylactic central neck dissection on locoregional recurrence in patients undergoing hemithyroidectomy.Methods. A meta-analysis was performed of full-text publications published in English retrieved from the Embase database.Results. The rate of regional recurrence in the central compartment after hemithyroidectomy, with or without prophylactic central neck dissection, was 0.17% and 1.78%, respectively. This difference was statistically significant. Recurrence in the lateral compartment or contralateral thyroid was not affected by prophylactic central neck dissection; the overall rate of recurrence was 1.3% and 5.4%, respectively.Conclusion. Prophylactic central neck dissection significantly reduced the risk of recurrence in the central compartment in patients undergoing hemithyroidectomy.

Prophylactic Central Neck Dissection in Papillary Thyroid Carcinoma: All Risks, No Reward

2021 ◽  
Vol 264 ◽  
pp. 230-235
Author(s):  
Jonathan Dismukes ◽  
Jessica Fazendin ◽  
Ruth Obiarinze ◽  
Gianina C. Hernández Márquez ◽  
Kimberly M Ramonell ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Neck Dissection ◽  
Central Neck Dissection ◽  
Central Neck ◽  
Papillary Thyroid ◽  
Prophylactic Central Neck Dissection

Prophylactic Central Neck Dissection for Clinically Node‐Negative Papillary Thyroid Carcinoma

2021 ◽  
Author(s):  
Khaled M. Alsubaie ◽  
Hemail M. Alsubaie ◽  
Faisal R. Alzahrani ◽  
Mohammad A. Alessa ◽  
Sherif K. Abdulmonem ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Neck Dissection ◽  
Central Neck Dissection ◽  
Central Neck ◽  
Papillary Thyroid ◽  
Node Negative ◽  
Prophylactic Central Neck Dissection
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