Comparing the outcome of different biologically derived acellular dermal matrices in implant based immediate breast reconstruction: A Meta-analysis of the literature

2018 ◽  
Vol 44 (6) ◽  
pp. 873
Author(s):  
Yew Loong Loo ◽  
Pragash Kamalathevan ◽  
Peng Sheng Ooi ◽  
Afshin Mosahebi
Author(s):  
Mohammed Attallah Alharbi ◽  
Fahad K. Aljindan ◽  
Reshan Mane Al Reshan ◽  
Khalid Dakhelallah Almutairi ◽  
Fatimah Mofeed Almosabh ◽  
...  

There has been an increase in invasive breast carcinoma which many times end up with a mastectomy. The psychological effects of mastectomy can be overwhelming, urging the need for optimum breast reconstruction procedures. Acellular dermal matrices are widely used nowadays due to their favorable outcomes with a few complications. In this study, we review the literature to explore the different types used, cons, and pros of this procedure. Databases like PubMed, Medline, Web of science, Embase, Google scholar, and Scopus were used and searched for following terms “implant-based reconstruction” or “breast reconstruction” or “acellular dermal matrix”. All studies that discuss the use of acellular dermal matrices for breast reconstructive surgery were included. Acellular dermal matrices may allow a relatively easy, affordable and time-efficient breast reconstructive surgery. They are associated with less incidence of infection and capsular contracture making them an excellent fit for most procedures. However, m ore studies are needed to help understand possible risk factors, and complications and how to avoid them.


Medicina ◽  
2020 ◽  
Vol 56 (6) ◽  
pp. 256 ◽  
Author(s):  
Roberto Cuomo

Background and objectives: Breast cancer treatment has deeply changed in the last fifty years. Acellular dermal matrices (ADMs) were introduced for breast reconstruction, with encouraging results, but with conflicting reports too. The present paper aims to summarize the current data on breast reconstruction using acellular dermal matrices. Materials and Methods: We reviewed the literature regarding the use of ADM-assisted implant-based breast reconstruction. Results: The main techniques were analyzed and described. Conclusions: Several authors have recently reported positive results. Nevertheless, an increased complications’ rate has been reported by other authors. Higher cost compared to not-ADM-assisted breast reconstruction is another concern.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Luigi Valdatta ◽  
Anna Giulia Cattaneo ◽  
Igor Pellegatta ◽  
Stefano Scamoni ◽  
Anna Minuti ◽  
...  

The increasing use of commercially available acellular dermis matrices for postmastectomy breast reconstruction seems to have simplified the surgical procedure and enhanced the outcome. These materials, generally considered to be highly safe or with only minor contraindications due to the necessary manipulation in preparatory phases, allow an easier one-phase surgical procedure, in comparison with autologous flaps, offering a high patient satisfaction. Unfortunately, the claim for a higher rate of complications associated with irradiation at the implant site, especially when the radiation therapy was given before the reconstructive surgery, suggested a careful behaviour when this technique is preferred. However, this hypothesis was never submitted to a crucial test, and data supporting it are often discordant or incomplete. To provide a comprehensive analysis of the field, we searched and systematically reviewed papers published after year 2005 and registered clinical trials. On the basis of a meta-analysis of data, we conclude that the negative effect of the radiotherapy on the breast reconstruction seems to be evident even in the case of acellular dermis matrices aided surgery. However, more trials are needed to make solid conclusions and clarify the poor comprehension of all the factors negatively influencing outcome.


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