Biochemical Recurrence After Robot-assisted Radical Prostatectomy in a European Single-centre Cohort with a Minimum Follow-up Time of 5 Years

2012 ◽  
Vol 62 (5) ◽  
pp. 768-774 ◽  
Author(s):  
Prasanna Sooriakumaran ◽  
Leif Haendler ◽  
Tommy Nyberg ◽  
Henrik Gronberg ◽  
Andreas Nilsson ◽  
...  
Urology ◽  
2012 ◽  
Vol 79 (1) ◽  
pp. 133-138 ◽  
Author(s):  
Nazareno Suardi ◽  
Vincenzo Ficarra ◽  
Pieter Willemsen ◽  
Peter De Wil ◽  
Andrea Gallina ◽  
...  

2010 ◽  
Vol 58 (6) ◽  
pp. 838-846 ◽  
Author(s):  
Mani Menon ◽  
Mahendra Bhandari ◽  
Nilesh Gupta ◽  
Zhaoli Lane ◽  
James O. Peabody ◽  
...  

2018 ◽  
Vol 25 (12) ◽  
pp. 1006-1014 ◽  
Author(s):  
Ali Abdel Raheem ◽  
Ki Don Chang ◽  
Mohammed Jayed Alenzi ◽  
Won Sik Ham ◽  
Woong Kyu Han ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tae Young Shin ◽  
Yong Seong Lee

Abstract Various neurovascular bundle-sparing techniques have been introduced to maximize recovery of erectile function after robot-assisted radical prostatectomy (RARP). The clipless intrafascial neurovascular bundle-sparing technique aims to preserve periprostatic structures and neurovascular bundles as much as possible by avoiding clipping of the vascular pedicles. This study reports 1-year functional and oncologic outcomes and postoperative complications in 105 patients with intact preoperative erectile function who underwent a modified clipless intrafascial neurovascular bundle-sparing RARP. Intact erectile function was defined as score ≥ 21 on the Sexual Health Inventory for Men questionnaire or ability to have sexual intercourse. Median follow-up was 26.5 months (IQR 15.25–48). Postoperative erectile function recovery rates were 71.4%, 81.9%, 88.6%, 92.4%, and 94.3% at 1, 3, 6, 9, and 12 months, respectively. The rate of positive surgical margins was 16.2% overall and 11.8% in patients with stage pT2 disease. The biochemical recurrence rate was 6.7% overall. The modified clipless intrafascial neurovascular bundle-sparing technique is safe and feasible and can achieve excellent recovery of erectile function after RARP. Further large-scale prospective comparative studies are warranted.


2011 ◽  
Vol 10 (2) ◽  
pp. 154
Author(s):  
N. Suardi ◽  
P. Willemsen ◽  
E. Pauwels ◽  
P. De Wil ◽  
G. De Naeyer ◽  
...  

2018 ◽  
Vol 4 (3) ◽  
pp. 351-359 ◽  
Author(s):  
Prabhakar Rajan ◽  
Anna Hagman ◽  
Prasanna Sooriakumaran ◽  
Tommy Nyberg ◽  
Anna Wallerstedt ◽  
...  

2014 ◽  
Vol 115 (1) ◽  
pp. 106-113 ◽  
Author(s):  
Prasanna Sooriakumaran ◽  
Achilles Ploumidis ◽  
Tommy Nyberg ◽  
Mats Olsson ◽  
Olof Akre ◽  
...  

2021 ◽  
Vol 11 (9) ◽  
pp. 912
Author(s):  
Young Chul Yoo ◽  
Won Sik Jang ◽  
Ki Jun Kim ◽  
Jung Hwa Hong ◽  
Sunmo Yang ◽  
...  

The usage of dexmedetomidine during cancer surgery in current clinical practice is debatable, largely owing to the differing reports of its efficacy based on cancer type. This study aimed to investigate the effects of dexmedetomidine on biochemical recurrence (BCR) and radiographic progression in patients with prostate cancer, who have undergone robot-assisted laparoscopic radical prostatectomy (RALP). Using follow-up data from two prospective randomized controlled studies, BCR and radiographic progression were compared between individuals who received dexmedetomidine (n = 58) and those who received saline (n = 56). Patients with complete follow-up records between July 2013 and June 2019 were enrolled in this study. There were no significant between-group differences in the number of patients who developed BCR and those who showed positive radiographic progression. Based on the Cox regression analysis, age (p = 0.015), Gleason score ≥ 8 (p < 0.001), and pathological tumor stage 3a and 3b (both p < 0.001) were shown to be significant predictors of post-RALP BCR. However, there was no impact on the dexmedetomidine or control groups. Low-dose administration of dexmedetomidine at a rate of 0.3–0.4 μg/kg/h did not significantly affect BCR incidence following RALP. In addition, no beneficial effect was noted on radiographic progression.


Sign in / Sign up

Export Citation Format

Share Document